ReviewIn vitro cellular & developmental biology : journal of the Tissue Culture Association1990
Frontiers in mammalian cell culture.
Review in In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 69 citations in OpenAlex.
- Coating materials enhance urochordate primary cell culture adherence.In vitro cellular & developmental biology. Animal · 2026Article
- Animal-cell culture media: History, characteristics, and current issues.Reproductive medicine and biology · 2017Review
- Proteomic study of different culture medium serum volume fractions on RANKL-dependent RAW264.7 cells differentiating into osteoclasts.Proteome science · 2015Article
- Keloid explant culture: a model for keloid fibroblasts isolation and cultivation based on the biological differences of its specific regions.International wound journal · 2010Article
- Albumin and mammalian cell culture: implications for biotechnology applications.Cytotechnology · 2010Article
- Tissue engineering of the vascular system: from capillaries to larger blood vessels.Medical & biological engineering & computing · 2000Review
- Simulated microgravity conditions enhance differentiation of cultured PC12 cells towards the neuroendocrine phenotype.In vitro cellular & developmental biology. Animal · 1998Article
- The prophylactic use of antibiotics in cell culture.Cytotechnology · 1995Article
- Framework for validation and implementation of in vitro toxicity tests.In vitro cellular & developmental biology. Animal · 1993Article
- Cell culture systems and in vitro toxicity testing. Technical report no. 4 of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT): technical workshop of June 13-15, 1990.Cytotechnology · 1992Article
- Thyroid hormone and apotransferrin regulation of growth hormone secretion by GH1 rat pituitary tumor cells in iron restricted serum-free defined medium.In vitro cellular & developmental biology : journal of the Tissue Culture Association · 1992Article
- A free-radical hypothesis for the instability and evolution of genotype and phenotype in vitro.Cytotechnology · 1992Review
- Concomitant proliferation and formation of a stratified epithelial sheet by explant outgrowth of epidermal keratinocytes from adult mice.In vitro cellular & developmental biology : journal of the Tissue Culture Association · 1991Article
- Functional differentiation of mouse uterine epithelial cells grown on collagen gels or reconstituted basement membranes.In vitro cellular & developmental biology : journal of the Tissue Culture Association · 1991Article
- Iron is deleterious to hormone-responsive pituitary cell growth in serum-free defined medium.In vitro cellular & developmental biology : journal of the Tissue Culture Association · 1991Article
- Technology and uses of cell cultures from the tissues and organs of bony fish.Cytotechnology · 1991Article
- Growth factors in invertebrate in vitro culture.In vitro cellular & developmental biology : journal of the Tissue Culture Association · 1991Review
- Nutrient optimization for high density biological production applications.Cytotechnology · 1991Review
- Development of serum-free media for the growth of human gastrointestinal adenocarcinoma xenografts as primary tissue cultures.Journal of cancer research and clinical oncology · 1991Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For the past 60 years, fundamental discoveries in eukaryotic biology using mammalian cell cultures have been significant but modest relative to the enormous potential. Combined with advances in technologies of cell and molecular biology, mammalian cell culture technology is becoming a major, if not essential tool, for fundamental discovery in eukaryotic biology. Reconstruction of the milieu for cells has progressed from simple salt solutions supporting brief survival of tissues outside the body to synthesis of the complete set of structurally defined nutrients, hormones and elements of the extracellular matrix needed to reconstruct complex tissues from cells. The isolation of specific cell types in completely defined environments reveals the true complexity of the mammalian cell and its environment as a dynamic interactive physiological unit. Cell cultures provide the tool for detection and dissection of the mechanism of action of cellular regulators and the genes that determine individual aspects of cell behavior. The technology underpins advances in virology, somatic cell genetics, endocrinology, carcinogenesis, toxicology, pharmacology, hematopoiesis and immunology, and is becoming a major tool in developmental biology, complex tissue physiology and production of unique mammalian cell-derived biologicals in industry.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.