It cuts two ways: microtubule loss during Alzheimer disease.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

23 citing papers in PubMed.

1. Astrocyte-enriched and cilia-related genetic signatures in dementia: A whole-exome sequencing study.General psychiatry · 2026
   Article
2. Targeting TTLL1 Alleviates Aβ-Induced Microtubule Disruption and TAU Pathology in Human iPSC-Derived Cortical Neurons.Pharmaceutics · 2026
   Article
3. Imaging microtubule dynamics: A new frontier in biomarker development for neurodegenerative diseases.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
   Review
4. Cutibacterium Acnes induces Alzheimer's disease-like pathology in brains of wistar rats through structural changes associated with microtubules.Behavioral and brain functions : BBF · 2024
   Article
5. Exploring microtubule dynamics in Alzheimer's disease: Longitudinal assessment using [Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
   Article
6. Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer's and Other Neurodegenerative Diseases.Nanomaterials (Basel, Switzerland) · 2024
   Article
7. A Combinational Therapy for Preventing and Delaying the Onset of Alzheimer's Disease: A Focus on Probiotic and Vitamin Co-Supplementation.Antioxidants (Basel, Switzerland) · 2024
   Review
8. XBP1 variant 1 promotes mitosis of cancer cells involving upregulation of the polyglutamylase TTLL6.Human molecular genetics · 2022
   Article
9. Preliminary mechanistic insights of a brain-penetrant microtubule imaging PET ligand in a tau-knockout mouse model.EJNMMI research · 2022
   Article
10. Natural Bioactive Products and Alzheimer's Disease Pathology: Lessons fromDiseases (Basel, Switzerland) · 2022
    Review
11. Sex-Related Motor Deficits in the Tau-P301L Mouse Model.Biomedicines · 2021
    Article
12. UNC-45A Is Highly Expressed in the Proliferative Cells of the Mouse Genital Tract and in the Microtubule-Rich Areas of the Mouse Nervous System.Cells · 2021
    Article
13. The microtubule cytoskeleton at the synapse.Neuroscience letters · 2021
    Review
14. Formaldehyde, Epigenetics, and Alzheimer's Disease.Chemical research in toxicology · 2019
    Review
15. DNA methylation variability in Alzheimer's disease.Neurobiology of aging · 2019
    Article
16. It's all about tau.Progress in neurobiology · 2019
    Review
17. New Insights Into the Pathogenesis of Alzheimer's Disease.Frontiers in neurology · 2019
    Review
18. Vesicular Axonal Transport is Modified In Vivo by Tau Deletion or Overexpression in Drosophila.International journal of molecular sciences · 2018
    Article
19. Microtubules in health and degenerative disease of the nervous system.Brain research bulletin · 2016
    Review
20. Stability properties of neuronal microtubules.Cytoskeleton (Hoboken, N.J.) · 2016
    Review

Corrections and comments

• Comment on
  Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin.2013

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as