Evidence map›Paper›PMID 24076611›Full record

ArticlePediatric emergency care2013

Emergency department crowding and younger age are associated with delayed corticosteroid administration to children with acute asthma.

Arpi Bekmezian, Christopher Fee, Sona Bekmezian, Judith H Maselli, Ellen Weber

Abstract read
In one paragraph

Article in Pediatric emergency care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Initial emergency department vital signs may predict PICU admission in pediatric patients presenting with asthma exacerbation.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023
    Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Clinical pathway improves pediatrics asthma management in the emergency department and reduces admissions.The Journal of asthma : official journal of the Association for the Care of Asthma · 2015
    Article
  10. A Report of an Asthma Pathway Leading to Improved Resource Use.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arpi BekmezianFrom the Departments of *Pediatrics, †Emergency Medicine, ‡School of Dentistry, and §Department of Medicine, University of California, San Francisco, San Francisco, CA.
Christopher Fee
Sona Bekmezian
Judith H Maselli
Ellen Weber

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
NCRR NIH HHS UL1 RR024131NCRR NIH HHS UL1RR024131
6 · The paper itself

Abstract

objectiveThis study aimed to identify factors associated with delayed or omission of indicated steroids for children seen in the emergency department (ED) for moderate-to-severe asthma exacerbation.

methodsThis was a retrospective study of pediatric (age ≤ 21 years) patients treated in a general academic ED from January 2006 to September 2011 with a primary diagnosis of asthma (International Classification of Diseases, Ninth Revision code 493.xx) and moderate-to-severe exacerbations. A moderate-to-severe exacerbation was defined as requiring 2 or more (or continuous) bronchodilators. We determined the proportion of visits in which steroids were inappropriately omitted or delayed (>1 hour from arrival). Multivariable logistic regression models were used to identify patient, physician, and system factors associated with delayed or omitted steroids.

resultsOf 1333 pediatric asthma ED visits, 817 were for moderate-to-severe exacerbation; 645 (79%) received steroids. Patients younger than 6 years (odds ratio [OR], 2.25; 95% confidence interval [CI], 1.19-4.24), requiring more bronchodilators (OR, 2.82; 95% CI, 2.10-3.79), initially hypoxic (OR, 2.78; 95% CI, 1.33-5.83), or tachypneic (OR, 1.52; 95% CI, 1.05-2.20) were more likely to receive steroids. Median time to steroid administration was 108 minutes (interquartile range, 65-164 minutes). Steroid administration was delayed in 502 visits (78%). Patients with hypoxia (OR, 1.91; 95% CI, 1.11-3.27) or tachypnea (OR, 1.82; 95% CI, 1.17-2.84) were more likely to receive steroids 1 hour or less of arrival, whereas children younger than 2 years (OR, 0.16; 95% CI, 0.07-0.35) and those arriving during periods of higher ED volume (OR, 0.79; 95% CI, 0.67-0.94) were less likely to receive timely steroids.

conclusionsIn this ED, steroids were underprescribed and frequently delayed for pediatric ED patients with moderate-to-severe asthma exacerbation. Greater ED volume and younger age are associated with delays. Interventions are needed to expedite steroid administration, improving adherence to National Institutes of Health asthma guidelines.

Indexed as

CrowdingEmergency Service, HospitalAcute DiseaseAdolescentAdrenal Cortex HormonesAge FactorsAnti-Asthmatic AgentsAsthmaBronchodilator AgentsChildChild, PreschoolDrug Administration ScheduleDrug Therapy, CombinationElectronic Health RecordsFemaleGuideline AdherenceAdrenal Cortex HormonesAnti-Asthmatic AgentsBronchodilator Agents

Identifiers

PMID24076611
PMCPMC3809097

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.