ArticleInfection and immunity1990
Tumor necrosis factor enhances neutrophil-mediated killing of Plasmodium falciparum.
Article in Infection and immunity, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 72 citations in OpenAlex.
- Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria.EMBO reports · 2022Article
- Hemozoin: a Complex Molecule with Complex Activities.Current clinical microbiology reports · 2021Article
- Using two phases of the CD4 T cell response to blood-stage murine malaria to understand regulation of systemic immunity and placental pathology in Plasmodium falciparum infection.Immunological reviews · 2020Review
- Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions.Nature microbiology · 2019Article
- Circulating Neutrophil Extracellular Traps and Neutrophil Activation Are Increased in Proportion to Disease Severity in Human Malaria.The Journal of infectious diseases · 2019Article
- Differential Gene Expression Profile of Human Neutrophils Cultured withJournal of immunology research · 2018Article
- Serum IL-4, IL-12 and TNF-alpha in malaria: a comparative study associating cytokine responses with severity of disease from the Coastal Districts of Odisha.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2014Article
- Oxidative stress in malaria.International journal of molecular sciences · 2012Review
- Pathogenesis of malaria revisited.Medical microbiology and immunology · 2012Review
- Article
- Babesia bovis-stimulated macrophages express interleukin-1beta, interleukin-12, tumor necrosis factor alpha, and nitric oxide and inhibit parasite replication in vitro.Infection and immunity · 2000Article
- Opsonization and phagocytosis of Plasmodium falciparum merozoites measured by flow cytometry.Clinical and diagnostic laboratory immunology · 2000Article
- Thiolated recombinant human tumor necrosis factor-alpha protects against Plasmodium berghei K173-induced experimental cerebral malaria in mice.Antimicrobial agents and chemotherapy · 1999Article
- Phagocytosis does not play a major role in naturally acquired transmission-blocking immunity to Plasmodium falciparum malaria.Infection and immunity · 1999Article
- Enhancement of neutrophil-mediated killing of Plasmodium falciparum asexual blood forms by fatty acids: importance of fatty acid structure.Infection and immunity · 1997Article
- Immunoglobulin E, a pathogenic factor in Plasmodium falciparum malaria.Infection and immunity · 1997Article
- Tumor necrosis factor primes neutrophils to kill Staphylococcus aureus by an oxygen-dependent mechanism and Plasmodium falciparum by an oxygen-independent mechanism.Infection and immunity · 1996Article
- A synthetic tumor necrosis factor-alpha agonist peptide enhances human polymorphonuclear leukocyte-mediated killing of Plasmodium falciparum in vitro and suppresses Plasmodium chabaudi infection in mice.The Journal of clinical investigation · 1995Article
- Neutrophils as effector cells of T-cell-mediated, acquired immunity in murine listeriosis.Immunology · 1994Article
- Anaemia and resistance to malaria in transgenic mice expressing human tumour necrosis factor.Immunology · 1994Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We developed a radiometric assay by which the antiplasmodial effects of phagocytic cells can be quantitated. This assay was used to examine the effects of recombinant human tumor necrosis factor alpha (TNF-alpha) on the killing of Plasmodium falciparum by human neutrophils. Data presented demonstrated that neutrophils engulf and destroy P. falciparum, but substantial killing of parasites required the presence of either heat-labile or heat-stable opsonins. While recombinant TNF-alpha at concentrations of 5 to 50,000 U/ml showed no direct effects on the parasite, this cytokine augmented the antimalarial activity of neutrophils at doses of 20 to 250 U/10(6) neutrophils. The results suggest that TNF-alpha is an important component of the immune phagocytic effector mechanisms which are involved in destruction of the malarial parasite.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.