ReviewParasitology international2014
Imaging Plasmodium immunobiology in the liver, brain, and lung.
Review in Parasitology international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Imaging malaria parasites across scales and time.Journal of microscopy · 2026Review
- The role of helminths and their antigens in cancer therapy: insights from cell line models.Infectious agents and cancer · 2024Review
- PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury.Nature communications · 2024Article
- Review
- Genetics of cerebral malaria: pathogenesis, biomarkers and emerging therapeutic interventions.Cell & bioscience · 2022Review
- PET Imaging of Translocator Protein as a Marker of Malaria-Associated Lung Inflammation.Infection and immunity · 2021Article
- G6pd-Deficient Mice Are Protected From Experimental Cerebral Malaria and Liver Injury by Suppressing Proinflammatory Response in the Early Stage ofFrontiers in immunology · 2021Article
- Intravital Imaging of Pulmonary Immune Response in Inflammation and Infection.Frontiers in cell and developmental biology · 2020Review
- Long-term effect of uncomplicated Plasmodium berghei ANKA malaria on memory and anxiety-like behaviour in C57BL/6 mice.Parasites & vectors · 2018Article
- The antimicrobial molecule trappin-2/elafin has anti-parasitic properties and is protective in vivo in a murine model of cerebral malaria.Scientific reports · 2017Article
- Pathogenesis of Plasmodium berghei ANKA infection in the gerbil (Meriones unguiculatus) as an experimental model for severe malaria.Parasite (Paris, France) · 2017Article
- Mesenchymal stromal cell therapy attenuated lung and kidney injury but not brain damage in experimental cerebral malaria.Stem cell research & therapy · 2015Article
- Towards genome-wide experimental genetics in the in vivo malaria model parasite Plasmodium berghei.Pathogens and global health · 2015Review
- Pathogenesis of cerebral malaria: new diagnostic tools, biomarkers, and therapeutic approaches.Frontiers in cellular and infection microbiology · 2015Review
- Endothelial-Leukocyte Interaction in Severe Malaria: Beyond the Brain.Mediators of inflammation · 2015Review
- Plasmodium cellular effector mechanisms and the hepatic microenvironment.Frontiers in microbiology · 2015Review
- Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier.PLoS pathogens · 2014Article
- Memory T cells maintain protracted protection against malaria.Immunology letters · 2014Review
- Real-time imaging reveals the dynamics of leukocyte behaviour during experimental cerebral malaria pathogenesis.PLoS pathogens · 2014Article
- Host matrix metalloproteinases in cerebral malaria: new kids on the block against blood-brain barrier integrity?Fluids and barriers of the CNS · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Plasmodium falciparum malaria is responsible for the deaths of over half a million African children annually. Until a decade ago, dynamic analysis of the malaria parasite was limited to in vitro systems with the typical limitations associated with 2D monocultures or entirely artificial surfaces. Due to extremely low parasite densities, the liver was considered a black box in terms of Plasmodium sporozoite invasion, liver stage development, and merozoite release into the blood. Further, nothing was known about the behavior of blood stage parasites in organs such as the brain where clinical signs manifest and the ensuing immune response of the host that may ultimately result in a fatal outcome. The advent of fluorescent parasites, advances in imaging technology, and availability of an ever-increasing number of cellular and molecular probes have helped illuminate many steps along the pathogenetic cascade of this deadly tropical parasite.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.