ArticleThe Lancet. Infectious diseases2014
The cascade of HIV care in British Columbia, Canada, 1996-2011: a population-based retrospective cohort study.
Article in The Lancet. Infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 4 of them syntheses that pooled it.
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Who cites it
107 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Child contact management in high tuberculosis burden countries: A mixed-methods systematic review.PloS one · 2017Pooled it
- The Tuberculosis Cascade of Care in India's Public Sector: A Systematic Review and Meta-analysis.PLoS medicine · 2016Pooled it
- Long-term Virological Outcomes of First-Line Antiretroviral Therapy for HIV-1 in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Pooled it
- The HIV care cascade: a systematic review of data sources, methodology and comparability.Journal of the International AIDS Society · 2015Pooled it
- Evaluating Fidelity to a Modified NIATx Process Improvement Strategy for Improving HIV Services in Correctional Facilities.The journal of behavioral health services & research · 2018Trial
- Cost-Effectiveness of the 'One4All' HIV Linkage Intervention in Guangxi Zhuang Autonomous Region, China.PloS one · 2016Trial
- HIV cascade, key indicators, and other epidemiological metrics in Australia (2004-2023): a retrospective analysis.The Lancet regional health. Western Pacific · 2026Article
- Strategies to improve retention in care among people living with HIV at health facilities in Manaus, Brazil: insight from health care providers.AIDS research and therapy · 2026Article
- Unsuppressed HIV viral load among people living with HIV by exposure category in British Columbia, Canada from 2005 to 2020: a population-based cohort study.BMC global and public health · 2025Article
- Recommendation on the use of viral load tests and exclusion of CD4 tests as proxies for HIV medical visits.Annals of epidemiology · 2025Article
- "One pastor advised him to stop taking HIV medication": Promoters and barriers to HIV care among gay, bisexual, and men who have sex with men living with HIV in Ghana.Research square · 2024Article
- Successful expanded clinic network collaboration and patient tracing for retention in HIV care.AIDS research and therapy · 2022Article
- Exploring the Barriers in the Uptake of the Dutch MRSA 'Search and Destroy' Policy Using the Cascade of Care Approach.Antibiotics (Basel, Switzerland) · 2022Article
- A two-day workshop reviewing Canadian provincial and national HIV care cascade indicators, reporting, challenges, and recommendations.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022Article
- An explanation of the 15-year trend and investigation of the tuberculosis cascade in Kurdistan province.Journal of clinical tuberculosis and other mycobacterial diseases · 2022Article
- Healthcare and treatment experiences among people diagnosed with HIV before and after a province-wide treatment as prevention initiative in British Columbia, Canada.BMC public health · 2022Article
- Evaluating the cascade of care for hypertension in Sierra Leone.Tropical medicine & international health : TM & IH · 2021Article
- Determinants of losses in the latent tuberculosis infection cascade of care in Brazil.BMJ global health · 2021Article
- Economic evaluation of HIV testing options for low-prevalence high-income countries: a systematic review.Health economics review · 2021Article
- Leaving no one behind? An equity analysis of the HIV care cascade among a cohort of people living with HIV in Manitoba, Canada.BMC public health · 2021Article
47 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors.
Funding
Abstract
backgroundThe cascade of HIV care has become a focal point for implementation efforts to maximise the individual and public health benefits of antiretroviral therapy. We aimed to characterise longitudinal changes in engagement with the cascade of HIV care in British Columbia, Canada, from 1996 to 2011.
methodsWe used estimates of provincial HIV prevalence from the Public Health Agency of Canada and linked provincial population-level data to define, longitudinally, the numbers of individuals in each of the eight stages of the cascade of HIV care (HIV infected, diagnosed, linked to HIV care, retained in HIV care, highly active antiretroviral therapy (HAART) indicated, on HAART, adherent to HAART, and virologically suppressed) in British Columbia from 1996 to 2011. We used sensitivity analyses to determine the sensitivity of cascade-stage counts to variations in their definitions.
findings13,140 people were classified as diagnosed with HIV/AIDS in British Columbia during the study period. We noted substantial improvements over time in the proportions of individuals at each stage of the cascade of care. Based on prevalence estimates, the proportion of unidentified HIV-positive individuals decreased from 49·0% (estimated range 36·2-57·5%) in 1996 to 29·0% (11·6-40·7%) in 2011, and the proportion of HIV-positive people with viral suppression reached 34·6% (29·0-43·1%) in 2011.
interpretationCareful mapping of the cascade of care is crucial to understanding what further efforts are needed to maximise the beneficial effects of available interventions and so inform efforts to contain the spread of HIV/AIDS.
fundingBritish Columbia Ministry of Health, US National Institute on Drug Abuse (National Institutes of Health).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.