Trial reportThe Journal of thoracic and cardiovascular surgery2014
Risk factors for prolonged length of stay after the stage 2 procedure in the single-ventricle reconstruction trial.
Trial report in The Journal of thoracic and cardiovascular surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Tricuspid Valve Repair Can Restore the Prognosis of Patients with Hypoplastic Left Heart Syndrome and Tricuspid Valve Regurgitation: A Meta-analysis.Pediatric cardiology · 2024Pooled it
- Survival to Stage II with Ventricular Dysfunction: Secondary Analysis of the Single Ventricle Reconstruction Trial.Pediatric cardiology · 2018Trial
- Trial
- Representation learning for the prediction of length of stay in infants with congenital heart diseases undergoing cardiac surgery.European heart journal. Digital health · 2026Article
- Post-operative practice patterns after the bidirectional Glenn surgery: a survey.Cardiology in the young · 2026Article
- Achieving an Optimal Outcome After Stage 1 Palliation for Hypoplastic Left Heart Syndrome and Variants: Frequency, Associated Factors, and Subsequent Outcomes.Journal of the American Heart Association · 2024Article
- Using machine learning to predict five-year transplant-free survival among infants with hypoplastic left heart syndrome.Scientific reports · 2024Article
- Risk of in-hospital Deterioration for Children with Single Ventricle Physiology.Pediatric cardiology · 2023Article
- A Comparison of Bidirectional Glenn vs. Hemi-Fontan Procedure: An Analysis of the Single Ventricle Reconstruction Trial Public Use Dataset.Pediatric cardiology · 2020Article
- Predicting and Surviving Prolonged Critical Illness After Congenital Heart Surgery.Critical care medicine · 2020Article
- Deep Learning for Improved Risk Prediction in Surgical Outcomes.Scientific reports · 2020Article
- Heart failure after the Norwood procedure: An analysis of the Single Ventricle Reconstruction Trial.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2018Article
- The Optimal Timing of Stage-2-Palliation After the Norwood Operation.The Annals of thoracic surgery · 2018Article
- Heart Failure in Pediatric Patients With Congenital Heart Disease.Circulation research · 2017Review
- Current Practices in the Timing of Stage 2 Palliation.World journal for pediatric & congenital heart surgery · 2017Article
- Three-dimensional rotational angiography in the assessment of vascular and airway compression in children after a cavopulmonary anastomosis.Pediatric cardiology · 2015Article
- Intraocular pressure in children after congenital heart surgery: A single-center study.Annals of pediatric cardiologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 17 institutions in 3 countries.
Funding
Abstract
backgroundThe single-ventricle reconstruction trial randomized patients with single right ventricle lesions to a modified Blalock-Taussig or right ventricle-to-pulmonary artery shunt at the Norwood. This analysis describes outcomes at the stage 2 procedure and factors associated with a longer hospital length of stay (LOS).
methodsWe examined the association of shunt type with stage 2 hospital outcomes. Cox regression and bootstrapping were used to evaluate risk factors for longer LOS. We also examined characteristics associated with in-hospital death.
resultsThere were 393 subjects in the analytic cohort. Median stage 2 procedure hospital LOS (8 days; interquartile range [IQR], 6-14 days), hospital mortality (4.3%), transplantation (0.8%), median ventilator time (2 days; IQR, 1-3 days), median intensive care unit LOS (4 days; IQR, 3-7 days), number of additional cardiac procedures or complications, and serious adverse events did not differ by shunt type. Longer LOS was associated (R(2) = 0.26) with center, longer post-Norwood LOS (hazard ratio [HR], 1.93 per log day; P < .001), nonelective timing of the stage 2 procedure (HR, 1.78; P < .001), and pulmonary artery (PA) stenosis (HR, 1.56; P < .001). By univariate analysis, nonelective stage 2 (65% vs 32%; P = .009), moderate or greater atrioventricular valve (AVV) regurgitation (75% vs 24%; P < .001), and AVV repair (53% vs 9%; P < .001) were among the risk factors associated with in-hospital death.
conclusionsNorwood LOS, PA stenoses, and nonelective stage 2 procedure, but not shunt type, are independently associated with longer LOS. Nonelective stage 2 procedure, moderate or greater AVV regurgitation, and need for AVV repair are among the risk factors for death.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.