Evidence map›Paper›PMID 24075272›Full record

ArticleSurgery2013

Predicting the need for urgent intubation in a surgical/trauma intensive care unit.

Amani D Politano, Lin M Riccio, Douglas E Lake, Craig G Rusin, Lauren E Guin, Christopher S Josef, Matthew T Clark, Robert G Sawyer, J Randall Moorman, James F Calland and 1 more

Open access · greenAbstract readValidation Study
In one paragraph

Article in Surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 48 citations in OpenAlex.

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  18. Data Science for Child Health.The Journal of pediatrics · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Amani D PolitanoDepartment of Surgery, University of Virginia Health System, Charlottesville, VA.
Lin M Riccio
Douglas E Lake
Craig G Rusin
Lauren E Guin
Christopher S Josef
Matthew T Clark
Robert G Sawyer
J Randall Moorman
James F Calland
Predictive Monitoring in Patients with Trauma (PreMPT) Group
Charlottesville Medical Research · USUniversity of Virginia Health System · US

Funding

Surgical Infectious Diseses and Transplantation Training GrantT32AI078875 · NIAID · UNIVERSITY OF VIRGINIA · PI SAWYER, ROBERT G · 2009 to 2013
$947k
NIAID NIH HHS T32 AI078875
6 · The paper itself

Abstract

backgroundAnalysis and modeling of data monitoring vital signs and waveforms in patients in a surgical/trauma intensive care unit (STICU) may allow for early identification and treatment of patients with evolving respiratory failure.

methodsBetween February 2011 and March 2012, data of vital signs and waveforms for STICU patients were collected. Every-15-minute calculations (n = 172,326) of means and standard deviations of heart rate (HR), respiratory rate (RR), pulse-oxygen saturation (SpO2), cross-correlation coefficients, and cross-sample entropy for HR-RR, RR-SpO2, and HR-SpO2, and cardiorespiratory coupling were calculated. Urgent intubations were recorded. Univariate analyses were performed for the periods <24 and ≥24 hours before intubation. Multivariate predictive models for the risk of unplanned intubation were developed and validated internally by subsequent sample and bootstrapping techniques.

resultsFifty unplanned intubations (41 patients) were identified from 798 STICU patients. The optimal multivariate predictive model (HR, RR, and SpO2 means, and RR-SpO2 correlation coefficient) had a receiving operating characteristic (ROC) area of 0.770 (95% confidence interval [CI], 0.712-0.841). For this model, relative risks of intubation in the next 24 hours for the lowest and highest quintiles were 0.20 and 2.95, respectively (15-fold increase, baseline risk 1.46%). Adding age and days since previous extubation to this model increased ROC area to 0.865 (95 % CI, 0.821-0.910).

conclusionAmong STICU patients, a multivariate model predicted increases in risk of intubation in the following 24 hours based on vital sign data available currently on bedside monitors. Further refinement could allow for earlier detection of respiratory decompensation and intervention to decrease preventable morbidity and mortality in surgical/trauma patients.

Indexed as

Emergency Medical ServicesVital SignsAgedCritical CareHumansIntensive Care UnitsIntubation, IntratrachealMiddle AgedModels, StatisticalProspective StudiesRespiratory InsufficiencyTertiary Care Centers

Identifiers

PMID24075272
PMCPMC3805718
OpenAlexW1971286943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.