ArticleJournal of biomechanics2013
Subject-specific knee joint geometry improves predictions of medial tibiofemoral contact forces.
Article in Journal of biomechanics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of the Associations Between Inverse Dynamics and Musculoskeletal Modeling to Investigate Joint Loading in a Clinical Environment.Frontiers in bioengineering and biotechnology · 2020Pooled it
- Trial
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- Predictors of knee joint loading after anterior cruciate ligament reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2017Trial
- From Joint Loading to Osteoarthritis: A Multiscale Review of Knee Mechanobiology and Digital Modelling.International journal of molecular sciences · 2026Review
- Joint Reaction Forces Decrease Following Total Knee Arthroplasty up to 12-Months Post-Surgery.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Article
- Computational biomechanics of human knee joint in maximum voluntary isometric extension with focus on the role of joint center positioning.Scientific reports · 2026Article
- How peak knee loads are affected by changing the mass of lower-limb body segments during walking.PLoS computational biology · 2025Article
- Decoding the Contribution of Shoulder and Elbow Mechanics to Barbell Kinematics and the Sticking Region in Bench and Overhead Press Exercises: A Link-Chain Model with Single- and Two-Joint Muscles.Journal of functional morphology and kinesiology · 2025Article
- Development of a personalized parametric finite element model of the knee: Evaluation of geometric variables affecting osteoarthritis progression.Journal of orthopaedics · 2025Article
- [Three-dimensional human-robot mechanics modeling for dual-arm nursing-care robot transfer based on individualized musculoskeletal multibody dynamics].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025Article
- Soft back exosuit controlled by neuro-mechanical modeling provides adaptive assistance while lifting unknown loads and reduces lumbosacral compression forces.Wearable technologies · 2025Article
- Tailored Multibody Tibiofemoral Joint Model for Precision Care.Applied bionics and biomechanics · 2025Article
- Evaluation of 3D Footprint Morphology of Knee-Related Muscle Attachments Based on CT Data Reconstruction: A Feasibility Study.Life (Basel, Switzerland) · 2024Article
- Effects of gait modifications on tissue-level knee mechanics in individuals with medial tibiofemoral osteoarthritis: A proof-of-concept study towards personalized interventions.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- The impact of anterior knee displacement on knee joint load during the forward bow step in Tai Chi.Frontiers in bioengineering and biotechnology · 2024Article
- Article
- Can a Musculoskeletal Model Adapted to Knee Implant Geometry Improve Prediction of 3D Contact Forces and Moments?Annals of biomedical engineering · 2023Article
- Simulated Tibiofemoral Joint Reaction Forces for Three Previously Studied Gait Modifications in Healthy Controls.Journal of biomechanical engineering · 2023Article
- Towards a validated musculoskeletal knee model to estimate tibiofemoral kinematics and ligament strains: comparison of different anterolateral augmentation procedures combined with isolated ACL reconstructions.Biomedical engineering online · 2023Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Estimating tibiofemoral joint contact forces is important for understanding the initiation and progression of knee osteoarthritis. However, tibiofemoral contact force predictions are influenced by many factors including muscle forces and anatomical representations of the knee joint. This study aimed to investigate the influence of subject-specific geometry and knee joint kinematics on the prediction of tibiofemoral contact forces using a calibrated EMG-driven neuromusculoskeletal model of the knee. One participant fitted with an instrumented total knee replacement walked at a self-selected speed while medial and lateral tibiofemoral contact forces, ground reaction forces, whole-body kinematics, and lower-limb muscle activity were simultaneously measured. The combination of generic and subject-specific knee joint geometry and kinematics resulted in four different OpenSim models used to estimate muscle-tendon lengths and moment arms. The subject-specific geometric model was created from CT scans and the subject-specific knee joint kinematics representing the translation of the tibia relative to the femur was obtained from fluoroscopy. The EMG-driven model was calibrated using one walking trial, but with three different cost functions that tracked the knee flexion/extension moments with and without constraint over the estimated joint contact forces. The calibrated models then predicted the medial and lateral tibiofemoral contact forces for five other different walking trials. The use of subject-specific models with minimization of the peak tibiofemoral contact forces improved the accuracy of medial contact forces by 47% and lateral contact forces by 7%, respectively compared with the use of generic musculoskeletal model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.