Evidence map›Paper›PMID 24074857›Full record

ArticleCell2013

Cerebral organoids in a dish: progress and prospects.

Marina Bershteyn, Arnold R Kriegstein

Abstract readComment
In one paragraph

Article in Cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Natural products as Zika antivirals.Medicinal research reviews · 2022
    Review
  5. Review
  6. Review
  7. Review
  8. Toxicity Assessment of SiOMolecules (Basel, Switzerland) · 2020
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Potential application of cell reprogramming techniques for cancer research.Cellular and molecular life sciences : CMLS · 2019
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Marina BershteynEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, 35 Medical Center Way, San Francisco, CA 94143, USA; University of California, San Francisco, San Francisco, CA 94143, USA.
Arnold R Kriegstein

Funding

Molecular and cellular mechanism of MicrocephalyR01NS072630 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRIEGSTEIN, ARNOLD · 2010 to 2014
$1.6M
NINDS NIH HHS R01 NS072630
6 · The paper itself

Abstract

A three-dimensional culture of cortical tissues derived from pluripotent stem cells offers an opportunity to model human brain development and disorders. In a recent issue of Nature, Lancaster et al. describe a new method for generating cerebral organoids in a dish and use it to model microcephaly.

Indexed as

Models, BiologicalAnimalsBrainHumansMicrocephalyOrganoidsTissue Culture Techniques

Identifiers

PMID24074857
PMCPMC5127703

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.