Evidence map›Paper›PMID 24074856›Full record

ArticleCell2013

Mitofusins: mighty regulators of metabolism.

Umut Ozcan

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Transcriptional profiling revealed the anti-proliferative effect of MFN2 deficiency and identified risk factors in lung adenocarcinoma.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  6. Review
  7. A temperature hypothesis of hypothalamus-driven obesity.The Yale journal of biology and medicine · 2014
    Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Umut OzcanDivision of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02130, USA. Electronic address: umut.ozcan@childrens.harvard.edu.
Boston Children's Hospital · US

Funding

Endoplasmic Reticulum Stress, Brain and ObesityR01DK098496 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI OZCAN, UMUT · 2013 to 2022
$4.6M
The In Vivo Role of JNK-1 and IRS-1 Ser307 Phosphorylation In Development of InsuR01DK081009 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI OZCAN, UMUT · 2008 to 2012
$1.7M
NIDDK NIH HHS R01DK081009NIDDK NIH HHS R01 DK098496NIDDK NIH HHS R01DK098496
6 · The paper itself

Abstract

Mitochondria are central regulators of cellular metabolism but how their function in a subset of cells affects whole-body energy balance is less understood. Two studies in this issue of Cell identify how diet-dependent modulation of mitochondrial fusion in specific neuronal circuits impact the metabolic status of an animal.

Indexed as

Endoplasmic Reticulum StressAnimalsFemaleGTP PhosphohydrolasesMaleMitochondriaNeuronsObesityGTP PhosphohydrolasesMfn1 protein, mouseMfn2 protein, mouse

Identifiers

PMID24074856
OpenAlexW2059584921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.