Trial reportBMC psychiatry2013
The EVIDENT-trial: protocol and rationale of a multicenter randomized controlled trial testing the effectiveness of an online-based psychological intervention.
Trial report in BMC psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Internet-based Depression Treatment
Effectiveness of Internet-based Depression Treatment (EVIDENT) in Severe Depression
Who cites it
25 citing papers in PubMed.
- Trial
- The Association of Therapeutic Alliance With Long-Term Outcome in a Guided Internet Intervention for Depression: Secondary Analysis From a Randomized Control Trial.Journal of medical Internet research · 2020Trial
- Trial
- Protocol for the ENCODE trial: evaluating a novel online depression intervention for persons with epilepsy.BMC psychiatry · 2017Trial
- Trial
- Public trust in genomic risk assessment for type 2 diabetes mellitus.Journal of genetic counseling · 2014Trial
- Effects of a Psychological Internet Intervention in the Treatment of Mild to Moderate Depressive Symptoms: Results of the EVIDENT Study, a Randomized Controlled Trial.Psychotherapy and psychosomaticsTrial
- Applying a mobile intervention for chronic insomnia in routine care: Study protocol for a multicenter randomized controlled trial.Internet interventions · 2025Article
- Healthcare effects and evidence robustness of reimbursable digital health applications in Germany: a systematic review.NPJ digital medicine · 2025Article
- A Web-Based Self-help Intervention for Coping With the Loss of a Partner: Protocol for Randomized Controlled Trials in 3 Countries.JMIR research protocols · 2022Article
- Digital health applications and the fast-track pathway to public health coverage in Germany: challenges and opportunities based on first results.BMC health services research · 2022Article
- Efficacy of a Web-Based Intervention for Depressive Disorders: Three-Arm Randomized Controlled Trial Comparing Guided and Unguided Self-Help With Waitlist Control.JMIR formative research · 2022Article
- Article
- Maintaining Outcomes of Internet-Delivered Cognitive-Behavioral Therapy for Depression: A Network Analysis of Follow-Up Effects.Frontiers in psychiatry · 2021Article
- Article
- It can't hurt, right? Adverse effects of psychotherapy in patients with depression.European archives of psychiatry and clinical neuroscience · 2019Article
- Health economic evaluation of a web-based intervention for depression: the EVIDENT-trial, a randomized controlled study.Health economics review · 2019Article
- Mental Health and Psychosocial Functioning Over the Lifespan of German Patients Undergoing Cardiac Catheterization for Coronary Artery Disease.Frontiers in psychiatry · 2018Article
- Defining and Predicting Patterns of Early Response in a Web-Based Intervention for Depression.Journal of medical Internet research · 2017Article
- [Internet-based interventions in the treatment of mental disorders : Overview, quality criteria, perspectives].Der Nervenarzt · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepressive disorders are among the leading causes of worldwide disability with mild to moderate forms of depression being particularly common. Low-intensity treatments such as online psychological treatments may be an effective way to treat mild to moderate depressive symptoms and prevent the emergence or relapse of major depression. METHODS/
designThis study is a currently recruiting multicentre parallel-groups pragmatic randomized-controlled single-blind trial. A total of 1000 participants with mild to moderate symptoms of depression from various settings including in- and outpatient services will be randomized to an online psychological treatment or care as usual (CAU). We hypothesize that the intervention will be superior to CAU in reducing depressive symptoms assessed with the Personal Health Questionnaire (PHQ-9, primary outcome measure) following the intervention (12 wks) and at follow-up (24 and 48 wks). Further outcome parameters include quality of life, use of health care resources and attitude towards online psychological treatments. DISCUSSION: The study will yield meaningful answers to the question of whether online psychological treatment can contribute to the effective and efficient prevention and treatment of mild to moderate depression on a population level with a low barrier to entry.
trial registrationTRIAL REGISTRATION NUMBER: NCT01636752.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.