Evidence map›Paper›PMID 24073633›Full record

ArticleEpidemiology and infection2014

Characterization of multi-drug resistant Mycobacterium tuberculosis from immigrants residing in the USA using Ion Torrent full-gene sequencing.

L T Daum, G W Fischer, J Sromek, M Khubbar, P Hunter, M S Gradus, S Bhattacharyya

Abstract read
In one paragraph

Article in Epidemiology and infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Article
  8. Antibiotic resistance mechanisms of Myroides sp.Journal of Zhejiang University. Science. B · 2016
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

L T DaumLonghorn Vaccines & Diagnostics, San Antonio, TX, USA.
G W FischerLonghorn Vaccines & Diagnostics, San Antonio, TX, USA.
J SromekCity of Milwaukee Health Department, Milwaukee, WI, USA.
M KhubbarCity of Milwaukee Health Department, Milwaukee, WI, USA.
P HunterCity of Milwaukee Health Department, Milwaukee, WI, USA.
M S GradusCity of Milwaukee Health Department, Milwaukee, WI, USA.
S BhattacharyyaCity of Milwaukee Health Department, Milwaukee, WI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summaryDrug-resistant Mycobacterium tuberculosis bacterium (MTB) is spreading worldwide. Three drug-resistant isolates were detected in Burmese, Hmong, and Indian immigrants currently residing in Milwaukee, Wisconsin, USA. Ion Torrent full-gene sequencing and complete genetic analysis was performed within 5 days and compared to results from traditional drug sensitivity testing (DST). Genetic characterization of seven, full-length resistance-associated genes revealed two MDR and one highly resistant strain with important drug-resistant mutations that were confirmed by traditional DST. The rapid turnaround from sample-to-sequence underscores the public health value of Ion Torrent full-gene sequencing of MDR/XDR genes from epidemiologically significant clinical isolates.

Indexed as

Antitubercular AgentsBacterial ProteinsBacteriological TechniquesChinaDrug Resistance, Multiple, BacterialEmigrants and ImmigrantsGenome, BacterialHigh-Throughput Nucleotide SequencingHumansIndiaMolecular Sequence DataMyanmarMycobacterium tuberculosisTuberculosis, Multidrug-ResistantWisconsinAntitubercular AgentsBacterial Proteins

Identifiers

PMID24073633
PMCPMC4045166

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.