Evidence map›Paper›PMID 24073395›Full record

ArticleBioMed research international2013

Primary immunodeficiency diseases at reference and high-specialty hospitals in the state of Guanajuato, Mexico.

Eduardo Guaní-Guerra, Ulises Noel García-Ramírez, Ana Isabel Jiménez-Romero, José Manuel Velázquez-Ávalos, Gabriela Gallardo-Martínez, Francisco-Javier Mendoza-Espinoza

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eduardo Guaní-GuerraDepartamento de Inmunología, Hospital Regional de Alta Especialidad del Bajío, Boulevard Milenio 130 San Carlos La Roncha, 37660 León, GTO, Mexico.
Ulises Noel García-Ramírez
Ana Isabel Jiménez-Romero
José Manuel Velázquez-Ávalos
Gabriela Gallardo-Martínez
Francisco-Javier Mendoza-Espinoza
Hospital Regional de Alta Especialidad del Bajío · MXInstitute for Social Security and Services for State Workers · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn general, primary immunodeficiency diseases (PIDs) are underdiagnosed in most countries. The objective of this study was to describe the frequency and clinical spectrum of PID in the most important tertiary hospitals in our region.

methodsAn observational, cross-sectional, with retrospective chart, review study was conducted. A total of 26 patients were included and grouped according to the updated classification of PIDs.

resultsPIDs spectra were as follows: predominantly antibody deficiency diseases were the most common category (65.38%), followed by other well-defined immunodeficiency syndromes (11.55%), congenital defects of phagocyte number and/or function (7.69%), complement deficiencies (3.85%), combined T- and B-cell immunodeficiencies (3.85%), and defects in innate immunity (3.85%). The mean time elapsed from the onset of symptoms to the reference and diagnosis by a tertiary hospital was of 4.65 ± 6.95 years.

conclusionsPredominant antibody deficiency disease was the most common group of PIDs, agreeing with international reports. Awareness of underdiagnosis by physicians is crucial for a prompt diagnosis and treatment, which in turn should improve the quality of life among patients with PIDs.

Indexed as

AdolescentChildFemaleHospitalsHumansImmunologic Deficiency SyndromesMaleMexico

Identifiers

PMID24073395
PMCPMC3773974
OpenAlexW2011215676

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.