Trial reportPloS one2013
High-incidence of human adenoviral co-infections in taiwan.
Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 29 citations in OpenAlex.
- Trial
- The value of primary care networks for molecular surveillance of paediatric respiratory infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Tiled-Amplicon Whole-Genome Sequencing Method Reveals Endemic Circulation of Human Adenovirus Type 3 in Japan.Viruses · 2026Article
- Human adenovirus in Taiwan, 2019-2023.Archives of virology · 2025Article
- High-Frequency Recombination of Human Adenovirus in Children with Acute Respiratory Tract Infections in Beijing, China.Viruses · 2024Article
- The APOBEC3B cytidine deaminase is an adenovirus restriction factor.PLoS pathogens · 2023Article
- Genomic analyses of human adenoviruses unravel novel recombinant genotypes associated with severe infections in pediatric patients.Scientific reports · 2021Article
- Prevalence, Distribution, and Genotypes of Adenovirus and Norovirus in the Puzi River and Its Tributaries and the Surrounding Areas in Taiwan.GeoHealth · 2021Article
- Infection of Bronchial Epithelial Cells by the Human Adenoviruses A12, B3, and C2 Differently Regulates the Innate Antiviral Effector APOBEC3B.Journal of virology · 2021Article
- [Clinical features of severe type 7 adenovirus pneumonia: an analysis of 45 cases].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Pediatric Infections byViruses · 2019Article
- Comparative study of clinical and epidemiological characteristics of major pediatric adenovirus epidemics in southern Taiwan.BMC infectious diseases · 2019Article
- Molecular characterization of human adenovirus associated with acute respiratory infections in Cameroon from 2011 to 2014.Virology journal · 2018Article
- Species differences in circulation and inflammatory responses in children with common respiratory adenovirus infections.Journal of medical virology · 2018Article
- Diagnosis of Pediatric Acute Adenovirus Infections: Is a Positive PCR Sufficient?The Pediatric infectious disease journal · 2016Article
- Molecular Epidemiology and Clinical Manifestations of Adenovirus Respiratory Infections in Taiwanese Children.Medicine · 2016Article
- Article
- Adenovirus infection in children with acute lower respiratory tract infections in Beijing, China, 2007 to 2012.BMC infectious diseases · 2015Article
- Protective efficacy of recombinant canine adenovirus type-2 expressing TgROP18 (CAV-2-ROP18) against acute and chronic Toxoplasma gondii infection in mice.BMC infectious diseases · 2015Article
- Adenovirus and herpesvirus diversity in free-ranging great apes in the Sangha region of the Republic Of Congo.PloS one · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRespiratory infections caused by adenovirus (HAdV) are common year round. Recently, a significant increase of adenoviral infections was observed in Taiwan.
objectiveTo understand the prevalence and molecular epidemiology of respiratory adenovirus circulating in Taiwan for the past decade. STUDY
designOne hundred and twenty-six human adenoviruses, isolated between 2002 to 2011, were characterized via DNA sequencing of the hexon and fiber genes. The nucleotide sequences were then compared by phylogenetic analysis.
resultsHAdV-B3 accounted for 64.3% (81/126) and peaked almost every year, whereas the sequences of hexon and fiber genes of HAdV-B3 were highly conserved in different years. A high incidence of co-infection of adenoviruses was observed (19.0%, 24/126); HAdV-B3 co-infected with HAdV-C2 was the most common combination (58.3%, 14/24). An additional interesting finding of repeated infection was noted in 10 children, all of whom showed first infection with adenovirus species HAdV-C, followed by species HAdV-B or HAdV-E.
conclusionsHAdV-B3 was the predominant type of respiratory adenovirus circulating in Taiwan over the past ten years. This merits further attention for vaccine development. Furthermore, the observed high-incidence of adenoviral co-infections along with repeated infections found in our study provides important epidemiological insights into adenovirus infections.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.