ArticlePloS one2013
Development of methodology for disability-adjusted life years (DALYs) calculation based on real-life data.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
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- Comparative disease burden of early-onset and late-onset type 2 diabetes in the U.S.: Evidence from NHANES 2003-2018.Journal of diabetes investigation · 2025Article
- Patient-centred estimation of multimorbidity in chronic disease populations: a novel approach integrating global burden of disease metrics and healthcare administrative data.Population health metrics · 2025Article
- Symptom response and episodic disability of long COVID in people with spinal cord injury: A case-control study.PloS one · 2024Article
- Case for investment in tobacco cessation: a population-based analysis in low- and middle-income countries.Revista panamericana de salud publica = Pan American journal of public health · 2022Article
- Estimating the disease burden of Korean type 2 diabetes mellitus patients considering its complications.PloS one · 2021Article
- Article
- The burden of health conditions across race and ethnicity for aging Americans: Disability-adjusted life years.Medicine · 2019Observational
- The burden of health conditions for middle-aged and older adults in the United States: disability-adjusted life years.BMC geriatrics · 2019Article
- The Burden of Functional Disabilities for Middle-Aged and Older Adults in the United States.The journal of nutrition, health & aging · 2019Article
- Moderate alcohol consumption is associated with lower chronic disease burden expressed in disability-adjusted life years: a prospective cohort study.European journal of epidemiology · 2017Article
- The impact of a healthy lifestyle on Disability-Adjusted Life Years: a prospective cohort study.BMC medicine · 2015Article
- Burden of disease measured by disability-adjusted life years and a disease forecasting time series model of scrub typhus in Laiwu, China.PLoS neglected tropical diseases · 2015Article
- Article
- Health-related quality of life (HRQoL) changes in South Australia: comparison of burden of disease morbidity and survey-based health utility estimates.Health and quality of life outcomes · 2014Article
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundDisability-Adjusted Life Years (DALYs) have the advantage that effects on total health instead of on a specific disease incidence or mortality can be estimated. Our aim was to address several methodological points related to the computation of DALYs at an individual level in a follow-up study.
methodsDALYs were computed for 33,507 men and women aged 20-70 years when participating in the EPIC-NL study in 1993-7. DALYs are the sum of the Years Lost due to Disability (YLD) and the Years of Life Lost (YLL) due to premature mortality. Premature mortality was defined as death before the estimated date of individual Life Expectancy (LE). Different methods to compute LE were compared as well as the effect of different follow-up periods using a two-part model estimating the effect of smoking status on health as an example.
resultsDuring a mean follow-up of 12.4 years, there were 69,245 DALYs due to years lived with a disease or premature death. Current-smokers had lost 1.28 healthy years of their life (1.28 DALYs 95%CI 1.10; 1.46) compared to never-smokers. The outcome varied depending on the method used for estimating LE, completeness of disease and mortality ascertainment and notably the percentage of extinction (duration of follow-up) of the cohort.
conclusionWe conclude that the use of DALYs in a cohort study is an appropriate way to assess total disease burden in relation to a determinant. The outcome is sensitive to the LE calculation method and the follow-up duration of the cohort.
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