Evidence map›Paper›PMID 24072937›Full record

ArticleMacromolecules2013

Fabrication of core-shell nanoparticles via controlled aggregation of semi-flexible conjugated polymer and hyaluronic acid.

Megan Twomey, Yoonmi Na, Zahilyn Roche, Eladio Mendez, Namuna Panday, Jin He, Joong Ho Moon

Abstract read
In one paragraph

Article in Macromolecules, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Megan TwomeyDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8 St., Miami, FL 33199, USA.
Yoonmi Na
Zahilyn Roche
Eladio Mendez
Namuna Panday
Jin He
Joong Ho Moon

Funding

Multiphoton Probes for Biomedical ImagingSC1GM092778 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI MOON, JOONGHO · 2011 to 2014
$829k
NIGMS NIH HHS SC1 GM092778
6 · The paper itself

Abstract

Core-shell conjugated polymer nanoparticles (CPNs) were fabricated by complexing a semi-flexible, primary amine-containing conjugated polymer (CP) with hyaluronic acid (HA). Flexibility introduced in the rigid rod conjugated backbone allows backbone reorganization to increase π-π interaction under ionic complexation, resulting in core-shell nanoparticles with a hydrophobic CP core wrapped with a HA shell. The core-shell nanoparticles exhibited no cellular toxicity and high cancer cell specificity with minimal binding to normal cells.

Identifiers

PMID24072937
PMCPMC3779919

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.