Evidence map›Paper›PMID 24072389›Full record

ReviewCell biology and toxicology2013

Molecular basis of active copper resistance mechanisms in Gram-negative bacteria.

Kinga Bondarczuk, Zofia Piotrowska-Seget

Open access · hybridAbstract readReview
In one paragraph

Review in Cell biology and toxicology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 249 citations in OpenAlex.

  1. Article
  2. Green and chemical synthesis of CuMicrobiology spectrum · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Copper-induced stress mechanisms inApplied and environmental microbiology · 2025
    Article
  7. Species-Specific Stress Responses to Selenium Nanoparticles inNanomaterials (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Experimental evolution ofMicrobiology spectrum · 2025
    Article
  12. Copper induced augmentation of antibiotic resistance in Acinetobacter baumannii MCC 3114.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
  13. Article
  14. Comparative metagenomics of wild and cultivatedCurrent research in microbial sciences · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Effects ofMicrobiology spectrum · 2024
    Article
  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kinga BondarczukDepartment of Microbiology, Faculty of Biology and Environment Protection, University of Silesia, Jagiellońska 28, 40-032, Katowice, Poland, kkrysta@us.edu.pl.
Zofia Piotrowska-Seget
University of Silesia in Katowice · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Copper is a metallic element that is crucial for cell metabolism; however, in extended concentrations, it is toxic for all living organisms. The dual nature of copper has forced organisms, including bacteria, to keep a tight hold on cellular copper content. This challenge has led to the evolution of complex mechanisms that on one hand enable them to deliver the essential element and on the other to protect cells against its toxicity. Such mechanisms have been found in both eukaryotic and prokaryotic cells. In bacteria a number of different systems such as extra- and intracellular sequestration, enzymatic detoxification, and metal removal from the cell enabling them to survive in the presence of high concentration of copper have been identified. Gram-negative bacteria, due to their additional compartment, need to deal with both cytoplasmic and periplasmic copper. Therefore, these bacteria have evolved intricate and precisely regulated systems which interact with each other. In this review the active mechanisms of copper resistance at their molecular level are discussed.

Indexed as

Amino Acid SequenceCopperGram-Negative BacteriaInactivation, MetabolicCopper

Identifiers

PMID24072389
PMCPMC3847284
OpenAlexW2022534102

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.