Evidence map›Paper›PMID 24071962›Full record

ReviewJournal of perinatology : official journal of the California Perinatal Association2013

Non-immune hydrops fetalis caused by herpes simplex virus type 2 in the setting of recurrent maternal infection.

K M Pfister, M R Schleiss, R C Reed, T N George

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Journal of perinatology : official journal of the California Perinatal Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Neonatal Herpes Simplex Viral Infections and Acyclovir: An Update.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

K M PfisterDivision of Neonatology, Department of Pediatrics, University of Minnesota Amplatz Children's Hospital, Minneapolis, MN, USA.
M R Schleiss
R C Reed
T N George
University of Minnesota · US

Funding

Viral Immunomodulation and Rational CMV Vaccine DesignR01HD044864 · NICHD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI GEBALLE, ADAM P., MCVOY, MICHAEL A · 2003 to 2015
$4.5M
Bedside-to-Bench Research Training for Pediatric Infectious Diseases FellowsT32HD068229 · NICHD · UNIVERSITY OF MINNESOTA · PI SCHLEISS, MARK R. · 2011 to 2015
$650k
NICHD NIH HHS HD044864NICHD NIH HHS HD068229
6 · The paper itself

Abstract

We report a case of non-immune hydrops fetalis (NIHF) caused by herpes simplex virus type 2 (HSV-2) in an infant whose mother had recurrent HSV-2 infection. In spite of prematurity, severe disseminated infection and hydrops, the infant survived and was neurologically intact. HSV-2-induced NIHF is extremely rare, particularly in the setting of recurrent maternal infection, and this case is, to our knowledge, the first report of a surviving infant. HSV-2 should be considered in the differential diagnosis of NIHF and early initiation of empiric acyclovir therapy is recommended in this setting, pending the results of virologic diagnostic tests.

Indexed as

AcyclovirAntiviral AgentsExtraembryonic MembranesFemaleHerpes GenitalisHumansHydrops FetalisInfant, NewbornInfant, PrematureInfant, Premature, DiseasesMalePregnancyPregnancy Complications, InfectiousPremature Rupture of Fetal MembranesRecurrenceYoung AdultAcyclovirAntiviral Agents

Identifiers

PMID24071962
OpenAlexW1997593014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.