Evidence map›Paper›PMID 24070826›Full record

ArticleUltrasonics2014

Osteoporosis detection in postmenopausal women using axial transmission multi-frequency bone ultrasonometer: clinical findings.

Vladimir Egorov, Alexey Tatarinov, Noune Sarvazyan, Randee Wood, Leonid Magidenko, Shreyasee Amin, Sundeep Khosla, Richard J Ruh, Jennifer M Ruh, Armen Sarvazyan

Abstract readMulticenter Study
In one paragraph

Article in Ultrasonics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Axial Transmission: Techniques, Devices and Clinical Results.Advances in experimental medicine and biology · 2022
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Ultrasound to assess bone quality.Current osteoporosis reports · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vladimir EgorovArtann Laboratories, Trenton, NJ 08618, USA. Electronic address: vegorov@artannlabs.com.
Alexey TatarinovArtann Laboratories, Trenton, NJ 08618, USA.
Noune SarvazyanArtann Laboratories, Trenton, NJ 08618, USA.
Randee WoodArtann Laboratories, Trenton, NJ 08618, USA.
Leonid MagidenkoHealth Smart Medical Center, Philadelphia, PA 19115, USA.
Shreyasee AminMayo Clinic, Rochester, MN 55905, USA.
Sundeep KhoslaMayo Clinic, Rochester, MN 55905, USA.
Richard J RuhCatholic Health, Sisters of Charity Hospital, Buffalo, NY 14214, USA.
Jennifer M RuhCatholic Health, Sisters of Charity Hospital, Buffalo, NY 14214, USA.
Armen SarvazyanArtann Laboratories, Trenton, NJ 08618, USA.

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
PORTABLE ULTRASONOMETER for OSTEOPOROSIS ASSESSMENTR44AG017400 · NIA · ARTANN LABORATORIES, INC. · PI SARVAZYAN, ARMEN · 2001 to 2010
$2.5M
NCATS NIH HHS UL1 TR000135NIA NIH HHS R44 AG017400NIA NIH HHS R44AG017400
6 · The paper itself

Abstract

The objective of this study was to evaluate if the Bone UltraSonic Scanner (BUSS) can detect osteoporosis in postmenopausal women. BUSS is an axial transmission multi-frequency ultrasonometer for acquisition of wave propagation profiles along the proximal anterior tibia. We derived 10 diagnostically significant BUSS parameters that were then compared with the DXA spine T-score, which was used in this study as the "gold standard" for the assessment of osteoporosis (T-score<-2.5). BUSS wave parameters were studied in 331 postmenopausal women examined by 9 trained operators at 3 clinical sites with use of 3 devices. The efficiency of each BUSS parameter in osteoporosis detection was assessed using a receiver operating characteristic curve analysis. Area under the curve (AUC) for each of 10 parameters ranged from 58.1% to 70.2%. Using these parameters a linear classifier was derived which provided at its output 83.0% AUC, 87.7% sensitivity and 63.2% specificity to DXA-identified osteoporosis. The results of this study confirm BUSS's capability to detect osteoporosis in postmenopausal women.

Indexed as

Absorptiometry, PhotonAgedAged, 80 and overBody Mass IndexBone DensityBone Diseases, MetabolicEquipment DesignFemaleHumansMiddle AgedOsteoporosis, PostmenopausalSensitivity and SpecificityUltrasonographyAxial scanningBone quantitative ultrasoundMulti-frequencyOsteoporosisWave propagation parameters

Identifiers

PMID24070826
PMCPMC3951708

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.