ReviewAdvances in immunology2013
Pathological consequence of misguided dendritic cell differentiation in histiocytic diseases.
Review in Advances in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 77 citations in OpenAlex.
- Blood MMP-7 and TNF-α levels as potential prognostic biomarkers for adult pulmonary Langerhans cell histiocytosis.Scientific reports · 2026Article
- Article
- Review
- Anti-LGI1 encephalitis and Langerhans cell histiocytosis: Two associated entities? A case report.Heliyon · 2024Article
- Giant Juvenile Xanthogranuloma Co-Occurring with Langerhans Cell Histiocytosis.The journal of pediatrics: X · 2023Article
- Adult Langerhans Cell Histiocytosis and the Skeleton.Journal of clinical medicine · 2022Review
- Article
- Immune Thrombocytopenia Revealing Enriched IgG-4 Peri-Renal Rosai-Dorfman Disease Successfully Treated with Rituximab: A Case Report and Literature Review.Frontiers in medicine · 2021Article
- Immune Microenvironment in Langerhans Cell Histiocytosis: Potential Prognostic Indicators.Frontiers in oncology · 2021Article
- Primary Oro-Facial Manifestations of Langerhans Cell Histiocytosis in Pediatric Age: A Bi-Institutional Retrospective Study on 45 Cases.Children (Basel, Switzerland) · 2020Article
- A neonate with Langerhans cell histiocytosis presenting as blueberry muffin rash: Case report and review of the literature.SAGE open medical case reports · 2020Article
- Epigenomics and Single-Cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis.Cancer discovery · 2019Article
- Primary oral manifestation of Langerhans cell histiocytosis refractory to conventional therapy but susceptible to BRAF-specific treatment: a case report and review of the literature.Therapeutic advances in medical oncology · 2019Article
- Langerhans cell histiocytosis in adults is associated with a high prevalence of hematologic and solid malignancies.Cancer medicine · 2019Article
- Resolved heart tamponade and controlled exophthalmos, facial pain and diabetes insipidus due to Erdheim-Chester disease.BMJ case reports · 2018Article
- Langerhans cell histiocytosis presenting as Crohn's disease: a case report.International journal of colorectal disease · 2018Article
- Clinical Research of Pulmonary Langerhans Cell Histiocytosis in Children.Chinese medical journal · 2018Article
- Bone metabolism in Langerhans cell histiocytosis.Endocrine connections · 2018Review
- CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions.Cancer · 2018Article
- Outcome After Radiation Therapy for Langerhans Cell Histiocytosis Is Dependent on Site of Involvement.International journal of radiation oncology, biology, physics · 2018Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
Abstract
Histiocytic disorders represent a group of complex pathologies characterized by the accumulation of histiocytes, an old term for tissue-resident macrophages and dendritic cells. Langerhans cell histiocytosis is the most frequent of histiocytosis in humans and has been thought to arise from the abnormal accumulation of epidermal dendritic cells called Langerhans cells. In this chapter, we discuss the origin and differentiation of Langerhans cells and dendritic cells and present accumulated evidence that suggests that Langerhans cell histiocytosis does not result from abnormal Langerhans cell homeostasis but rather is a consequence of misguided differentiation programs of myeloid dendritic cell precursors. We propose reclassification of Langerhans cell histiocytosis, juvenile xanthogranuloma, and Erdheim-Chester disease as inflammatory myeloid neoplasias.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.