ArticleAnalytical chemistry2013
DNA detection using origami paper analytical devices.
Article in Analytical chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Fluorescence origami paper-based analytical device based on strand displacement assay for SARS-CoV-2 cDNA detection.Mikrochimica acta · 2025Article
- Paper-Based Vertical Flow Assays for in Vitro Diagnostics and Environmental Monitoring.ACS sensors · 2025Review
- Sustainable Sensing with Paper Microfluidics: Applications in Health, Environment, and Food Safety.Biosensors · 2024Review
- Low-cost, portable, on-site fluorescent detection of As(III) by a paper-based microfluidic device based on aptamer and smartphone imaging.Mikrochimica acta · 2023Article
- Visible-light and near-infrared fluorescence and surface-enhanced Raman scattering point-of-care sensing and bio-imaging: a review.Chemical Society reviews · 2022Review
- [Applications of microfluidic paper-based chips in environmental analysis and detection].Se pu = Chinese journal of chromatography · 2021Article
- Increasing the packing density of assays in paper-based microfluidic devices.Biomicrofluidics · 2021Review
- Ultrasensitive cloth-based microfluidic chemiluminescence detection of Listeria monocytogenes hlyA gene by hemin/G-quadruplex DNAzyme and hybridization chain reaction signal amplification.Analytical and bioanalytical chemistry · 2020Article
- Monitoring cellulose oxidation for protein immobilization in paper-based low-cost biosensors.Mikrochimica acta · 2020Article
- A Simple Imaging Device for Fluorescence-Relevant Applications.Micromachines · 2018Article
- Laminated Copper Nanocluster Incorporated Antioxidative Paper Device with RGB System-Assisted Signal Improvement.Nanomaterials (Basel, Switzerland) · 2018Article
- Challenges in paper-based fluorogenic optical sensing with smartphones.Nano convergence · 2018Review
- An Open Software Platform for the Automated Design of Paper-Based Microfluidic Devices.Scientific reports · 2017Article
- Design of Flow Systems for Improved Networking and Reduced Noise in Biomolecular Signal Processing in Biocomputing and Biosensing Applications.Sensors (Basel, Switzerland) · 2016Article
- A Paper-Based "Pop-up" Electrochemical Device for Analysis of Beta-Hydroxybutyrate.Analytical chemistry · 2016Article
- Easily Fabricated Microfluidic Devices Using Permanent Marker Inks for Enzyme Assays.Micromachines · 2016Article
- A toolkit of thread-based microfluidics, sensors, and electronics for 3D tissue embedding for medical diagnostics.Microsystems & nanoengineering · 2016Article
- Low-voltage paper isotachophoresis device for DNA focusing.Lab on a chip · 2015Article
- Ultrasensitive visual read-out of nucleic acids using electrocatalytic fluid displacement.Nature communications · 2015Article
- Scalable low-cost fabrication of disposable paper sensors for DNA detection.ACS applied materials & interfaces · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We demonstrate the hybridization-induced fluorescence detection of DNA on an origami-based paper analytical device (oPAD). The paper substrate was patterned by wax printing and controlled heating to construct hydrophilic channels and hydrophobic barriers in a three-dimensional fashion. A competitive assay was developed where the analyte, a single-stranded DNA (ssDNA), and a quencher-labeled ssDNA competed for hybridization with a fluorophore-labeled ssDNA probe. Upon hybridization of the analyte with the fluorophore-labeled ssDNA, a linear response of fluorescence vs analyte concentration was observed with an extrapolated limit of detection <5 nM and a sensitivity relative standard deviation as low as 3%. The oPAD setup was also tested against OR/AND logic gates, proving to be successful in both detection systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.