ArticleBMC pulmonary medicine2013
Sarcoidosis with involvement of the paranasal sinuses - a retrospective analysis of 12 biopsy-proven cases.
Article in BMC pulmonary medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 26 citations in OpenAlex.
- Article
- Chronic rhinosinusitis revealing a nasal sarcoidosis: A case report.Radiology case reports · 2025Article
- Sinonasal Sarcoidosis: A Scoping Review of Demographics, Clinical Presentation, and Outcomes.Laryngoscope investigative otolaryngology · 2025Article
- Case report of osteolytic lesions in a patient with multisystem granulomatous disease.BMJ case reports · 2021Article
- Sarcoidosis of the paranasal sinuses.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Article
- Rare involvement of paranasal sinuses in sarcoidosis: case report and literature review.The Pan African medical journal · 2019Review
- CT and MR imaging of orbital inflammation.Neuroradiology · 2018Review
- Sinonasal sarcoidosis of the maxillary sinus and infraorbital nerve: a case report.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2015Article
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3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundExtrapulmonary involvement by sarcoidosis is observed in about 30-40% of patients with sarcoidosis. Little is known about the frequency and clinical characteristics of sinonasal sarcoidosis.
methodsWe retrospectively analyzed 12 cases of biopsy-proven sinonasal sarcoidosis. Patients were identified from a patient population of 1360 patients with sarcoidosis at the Outpatient Clinic for Sarcoidosis and Rare Lung Diseases at LungClinic Grosshansdorf, a tertiary care hospital for respiratory medicine.
resultsThe most frequent signs and symptoms were nasal polyps (4 cases), epistaxis (3 cases), nasal crusts (8 cases) and anosmia (5 cases). Pulmonary sarcoidosis of the patients was staged as stage I (n = 1) and stage II (n = 11) on chest radiographs. Spirometry was normal in 11 patients. 7 patients had a diffusion capacity of the lung for carbon monoxide of less than 90% of predicted. Other organs were affected in 8 patients. All patients received systemic corticosteroid treatment and most patients received topical steroids. 5 patients received steroid sparing agents. Repeated sinus surgery had to be performed in 4 patients.
conclusionsSinonasal involvement is a rare disease manifestation of sarcoidosis with a frequency slightly lower than 1% in our patient population. The clinical course of sinonasal sarcoidosis can be complicated by relapse despite systemic immunosuppressive treatment and repeated sinus surgery.
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