Evidence map›Paper›PMID 24069464›Full record

ReviewPLoS neglected tropical diseases2013

Atypical human infections by animal trypanosomes.

Philippe Truc, Philippe Büscher, Gérard Cuny, Mary Isabel Gonzatti, Jean Jannin, Prashant Joshi, Prayag Juyal, Zhao-Rong Lun, Raffaele Mattioli, Etienne Pays and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in PLoS neglected tropical diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it, 203 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Multi-Year Molecular Survey ofAnimals : an open access journal from MDPI · 2026
    Article
  4. Pathogens (Basel, Switzerland) · 2026
    Article
  5. International journal for parasitology. Parasites and wildlife · 2026
    Article
  6. Germline-targeted baboon apolipoprotein L-1 protects mice against African trypanosomes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Wildlife surveys detectCurrent research in parasitology & vector-borne diseases · 2026
    Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Review
  13. Transboundary and emerging diseases · 2025
    Article
  14. Species distribution and screening ofCurrent research in parasitology & vector-borne diseases · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Drug resistance in animal trypanosomiases: Epidemiology, mechanisms and control strategies.International journal for parasitology. Drugs and drug resistance · 2024
    Review
  20. Detection ofOpen veterinary journal · 2024
    Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 10 countries.

Philippe TrucInstitut de Recherche pour le Développement (IRD), UMR InterTryp 177 IRD/CIRAD, Campus International de Baillarguet, Montpellier, France.
Philippe Büscher
Gérard Cuny
Mary Isabel Gonzatti
Jean Jannin
Prashant Joshi
Prayag Juyal
Zhao-Rong Lun
Raffaele Mattioli
Etienne Pays
Pere P Simarro
Marta Maria Geraldes Teixeira
Louis Touratier
Philippe Vincendeau
Marc Desquesnes
Institut de Recherche pour le Développement · FRWorld Health Organization · CHFood and Agriculture Organization of the United Nations · ITGovernment Medical College · INGuru Angad Dev Veterinary and Animal Sciences University · INInstituut voor Tropische Geneeskunde · BEKasetsart University · THOrganisation Mondiale de la Santé Animale · FRSimón Bolívar University · VESun Yat-sen University · CNUniversidade de São Paulo · BRUniversité Libre de Bruxelles · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The two classical forms of human trypanosomoses are sleeping sickness due to Trypanosoma brucei gambiense or T. brucei rhodesiense, and Chagas disease due to T. cruzi. However, a number of atypical human infections caused by other T. species (or sub-species) have been reported, namely due to T. brucei brucei, T. vivax, T. congolense, T. evansi, T. lewisi, and T. lewisi-like. These cases are reviewed here. Some infections were transient in nature, while others required treatments that were successful in most cases, although two cases were fatal. A recent case of infection due to T. evansi was related to a lack of apolipoprotein L-I, but T. lewisi infections were not related to immunosuppression or specific human genetic profiles. Out of 19 patients, eight were confirmed between 1974 and 2010, thanks to improved molecular techniques. However, the number of cases of atypical human trypanosomoses might be underestimated. Thus, improvement, evaluation of new diagnostic tests, and field investigations are required for detection and confirmation of these atypical cases.

Indexed as

Clinical Laboratory TechniquesHumansTrypanosomaTrypanosomiasis

Identifiers

PMID24069464
PMCPMC3772015
OpenAlexW2140941348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.