SynthesisPloS one2013
Dietary cadmium intake and the risk of cancer: a meta-analysis.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Environmental endocrine disruptors and endometrial cancer risk: a systematic review and meta-analysis of cadmium and polychlorinated biphenyls, with emerging evidence on PFAS, phthalates, and bisphenols.Frontiers in oncology · 2026Pooled it
- Cadmium exposure and risk of breast cancer: A meta-analysis.Environmental research · 2023Pooled it
- Pooled it
- Association between dietary cadmium exposure and breast cancer risk: an updated meta-analysis of observational studies.Medical science monitor : international medical journal of experimental and clinical research · 2015Pooled it
- Trial
- A dietary-wide association study (DWAS) of environmental metal exposure in US children and adults.PloS one · 2014Trial
- Mitigation of cadmium toxicity in African catfish using biological Nano chitosan: insights into biochemical, genotoxic, and histopathological effects.BMC veterinary research · 2025Article
- Association of urinary cadmium and arsenic with gynecological cancers: Results from NHANES 2003-2018.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Total Effective Xenoestrogen Burden in Serum Samples and Risk of Endometrial Cancer in the Spanish Screenwide Case-Control Study.Environmental health perspectives · 2024Article
- Article
- Exposure to airborne cadmium and breast cancer stage, grade and histology at diagnosis: findings from the E3N cohort study.Scientific reports · 2021Article
- Levels of heavy metal cadmium in rice (Oryza sativa L.) produced in Taiwan and probabilistic risk assessment for the Taiwanese population.Environmental science and pollution research international · 2021Article
- A Narrative Review of the Role of Diet and Lifestyle Factors in the Development and Prevention of Endometrial Cancer.Cancers · 2021Review
- Developmental toxicity of cadmium in infants and children: a review.Environmental analysis, health and toxicology · 2021Article
- Effects of lead and cadmium on the immune system and cancer progression.Journal of environmental health science & engineering · 2020Review
- Genotoxic Effect of Lead and Cadmium on Workers at Wastewater Plant in Iraq.Journal of environmental and public health · 2020Article
- Association between dietary cadmium intake and early gastric cancer risk in a Korean population: a case-control study.European journal of nutrition · 2019Article
- A nongenomic mechanism for "metalloestrogenic" effects of cadmium in human uterine leiomyoma cells through G protein-coupled estrogen receptor.Archives of toxicology · 2019Article
- Potential interaction of cadmium chloride with pancreatic mitochondria: Implications for pancreatic cancer.International journal of molecular medicine · 2019Article
- Associations of Prenatal Exposure to Cadmium With Child Growth, Obesity, and Cardiometabolic Traits.American journal of epidemiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiet is a major source of cadmium intake among the non-smoking general population. Recent studies have determined that cadmium exposure may produce adverse health effects at lower exposure levels than previously predicted. We conducted a meta-analysis to combine and analyze the results of previous studies that have investigated the association of dietary cadmium intake and cancer risk.
methodsWe searched PubMed, EMBASE, and MEDLINE database for case-control and cohort studies that assessed the association of dietary cadmium intake and cancer risk. We performed a meta-analysis using eight eligible studies to summarize the data and summary relative risks (RRs) and 95% confidence intervals (CIs) were calculated using a random effects model.
resultsOverall, dietary cadmium intake showed no statistically significant association with cancer risk (RR = 1.10; 95% CI: 0.99-1.22, for highest vs. lowest dietary cadmium group). However, there was strong evidence of heterogeneity, and subgroup analyses were conducted using the study design, geographical location, and cancer type. In subgroup analyses, the positive associations between dietary cadmium intake and cancer risk were observed among studies with Western populations (RR = 1.15; 95% CI: 1.08-1.23) and studies investigating some hormone-related cancers (prostate, breast, and endometrial cancers).
conclusionOur analysis found a positive association between dietary cadmium intake and cancer risk among studies conducted in Western countries, particularly with hormone-related cancers. Additional experimental and epidemiological studies are required to verify our findings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.