Evidence map›Paper›PMID 24069234›Full record

ArticlePloS one2013

Age-specific average head template for typically developing 6-month-old infants.

Lisa F Akiyama, Todd R Richards, Toshiaki Imada, Stephen R Dager, Liv Wroblewski, Patricia K Kuhl

Abstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Baby brain atlases.NeuroImage · 2019
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Infants' brain responses to speech suggest analysis by synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lisa F AkiyamaUniversity Of Washington, Institute for Learning and Brain Sciences, Seattle, Washington, United States of America.
Todd R Richards
Toshiaki Imada
Stephen R Dager
Liv Wroblewski
Patricia K Kuhl

Funding

Cellular and molecular mechanisms governing cortical surface area overgrowth in iPSC-derived neural cells from longitudinally characterized individuals with autismR01HD055741 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph Piven · 2007 to 2026
$52.6M
UNIVERSITY OF WASHINGTON RESEARCH CORE CENTERP30DC004661 · NIDCD · UNIVERSITY OF WASHINGTON · PI PHILLIPS, JAMES O, TEMPEL, BRUCE L · 2000 to 2014
$11.1M
Development of Speech Perception and Brain PlasticityR01HD037954 · NICHD · UNIVERSITY OF WASHINGTON · PI KUHL, PATRICIA K · 1999 to 2011
$3.9M
A Longitudinal 3-D MRSI Study of Infants at High Risk for AutismR01HD065283 · NICHD · UNIVERSITY OF WASHINGTON · PI DAGER, STEPHEN R · 2009 to 2010
$445k
NICHD NIH HHS HD065283NICHD NIH HHS HD37954NICHD NIH HHS HD55741NICHD NIH HHS R01 HD037954NICHD NIH HHS R01 HD055741NICHD NIH HHS R01 HD065283NIDCD NIH HHS P30 DC004661NIDCD NIH HHS P30 DC04661
6 · The paper itself

Abstract

Due to the rapid anatomical changes that occur within the brain structure in early human development and the significant differences between infant brains and the widely used standard adult templates, it becomes increasingly important to utilize appropriate age- and population-specific average templates when analyzing infant neuroimaging data. In this study we created a new and highly detailed age-specific unbiased average head template in a standard MNI152-like infant coordinate system for healthy, typically developing 6-month-old infants by performing linear normalization, diffeomorphic normalization and iterative averaging processing on 60 subjects' structural images. The resulting age-specific average templates in a standard MNI152-like infant coordinate system demonstrate sharper anatomical detail and clarity compared to existing infant average templates and successfully retains the average head size of the 6-month-old infant. An example usage of the average infant templates transforms magnetoencephalography (MEG) estimated activity locations from MEG's subject-specific head coordinate space to the standard MNI152-like infant coordinate space. We also created a new atlas that reflects the true 6-month-old infant brain anatomy. Average templates and atlas are publicly available on our website (http://ilabs.washington.edu/6-m-templates-atlas).

Indexed as

Child DevelopmentAge FactorsBrainCephalometryFemaleHeadHumansImage Processing, Computer-AssistedInfantMagnetoencephalographyMaleNeuroimaging

Identifiers

PMID24069234
PMCPMC3772014

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.