ReviewHepatitis monthly2013
The role of anesthetic drugs in liver apoptosis.
Review in Hepatitis monthly, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Experimental study of a novel tumstatin on C6 brain gliomaOncology letters · 2017Article
- Isoflurane anesthesia induces liver injury by regulating the expression of insulin-like growth factor 1.Experimental and therapeutic medicine · 2017Article
- The role of inhalational anesthetic drugs in patients with hepatic dysfunction: a review article.Anesthesiology and pain medicine · 2015Review
- Hepatoprotective effect of 17β-estradiol as antioxidant modulators against stress damage.Hepatitis monthly · 2015Article
- Hepatotoxicity of halogenated inhalational anesthetics.Iranian Red Crescent medical journal · 2014Review
- Volatile anesthetics in ischemic liver injury: enemy or friend?Hepatitis monthly · 2014Article
- Comparison of the Effects of Sevoflurane and Isoflurane During Liver Transplant Surgery on the Short-Term Cardiac, Hepatic, and Renal Outcome: A Randomized Clinical Trial.Iranian journal of pharmaceutical research : IJPRArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextThe modern practice of anesthesia is highly dependent ona group of anesthetic drugs which many of them are metabolized in the liver. EVIDENCE ACQUISITION: The liver, of course, usually tolerates this burden. However, this is not always an unbroken rule. Anesthetic induced apoptosis has gained great concern during the last years; especially considering the neurologic system.
resultsHowever, we have evidence that there is some concern regarding their effects on the liver cells. Fortunately not all the anesthetics are blamed and even some could be used safely, based on the available evidence.
conclusionsBesides, there are some novel agents, yet under research, which could affect the future of anesthetic agents' fate regarding their hepatic effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.