Evidence map›Paper›PMID 24068857›Full record

ArticleMaterials science & engineering. R, Reports : a review journal2013

Nanoparticles for Improving Cancer Diagnosis.

Hongmin Chen, Zipeng Zhen, Trever Todd, Paul K Chu, Jin Xie

Abstract read
In one paragraph

Article in Materials science & engineering. R, Reports : a review journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
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  6. Article
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  8. Review
  9. Zinc Oxide Nanoparticles as Diagnostic Tool for Cancer Cells.International journal of biomaterials · 2022
    Article
  10. Review
  11. Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy.International journal of peptide research and therapeutics · 2021
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Medical imaging modalities using nanoprobes for cancer diagnosis: A literature review on recent findings.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hongmin ChenDepartment of Chemistry and Bio-Imaging Research Center, University of Georgia, 1001 Cedar Street, Athens, GA 30602.
Zipeng Zhen
Trever Todd
Paul K Chu
Jin Xie

Funding

Nanoplatform-based combinational therapy against breast cancer R00CA153772 · NCI · UNIVERSITY OF GEORGIA · PI XIE, JIN · 2011 to 2013
$710k
NCI NIH HHS R00 CA153772
6 · The paper itself

Abstract

Despite the progress in developing new therapeutic modalities, cancer remains one of the leading diseases causing human mortality. This is mainly attributed to the inability to diagnose tumors in their early stage. By the time the tumor is confirmed, the cancer may have already metastasized, thereby making therapies challenging or even impossible. It is therefore crucial to develop new or to improve existing diagnostic tools to enable diagnosis of cancer in its early or even pre-syndrome stage. The emergence of nanotechnology has provided such a possibility. Unique physical and physiochemical properties allow nanoparticles to be utilized as tags with excellent sensitivity. When coupled with the appropriate targeting molecules, nanoparticle-based probes can interact with a biological system and sense biological changes on the molecular level with unprecedented accuracy. In the past several years, much progress has been made in applying nanotechnology to clinical imaging and diagnostics, and interdisciplinary efforts have made an impact on clinical cancer management. This article aims to review the progress in this exciting area with emphases on the preparation and engineering techniques that have been developed to assemble "smart" nanoprobes.

Indexed as

bioconjugationbiomarkerscancer diagnosisimagingnanomedicinenanotechnologysurface modification

Identifiers

PMID24068857
PMCPMC3779646

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.