Trial reportAmerican journal of physiology. Regulatory, integrative and comparative physiology2013
Muscle metabolic responses during high-intensity intermittent exercise measured by (31)P-MRS: relationship to the critical power concept.
Trial report in American journal of physiology. Regulatory, integrative and comparative physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Programming Interval Training to Optimize Time-Trial Performance: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2021Pooled it
- Influence of beetroot juice supplementation on intermittent exercise performance.European journal of applied physiology · 2016Trial
- Delaying task failure in high-intensity exercise: a Pi-afferent-effort framework for targeted sports nutrition.Journal of the International Society of Sports Nutrition · 2026Review
- The Measurement and Application of Critical Speed and D' in Running: A Scoping Review.Sports medicine (Auckland, N.Z.) · 2026Article
- Human dorsiflexor muscles are resilient against voluntary activation failure following high-intensity interval exercise.European journal of applied physiology · 2026Article
- W' reconstitution modelling during intermittent exercise performed to task failure.European journal of applied physiology · 2026Article
- Performance Fatigability at Task Failure and Beyond: Distinct Patterns of Recovery Following Constant Load Versus Intermittent Cycling Exercise.International journal of exercise science · 2025Article
- Exercise- and diet-induced glycogen depletion impairs performance during one-legged constant-load, high-intensity exercise in humans.Frontiers in physiology · 2025Article
- The Characteristics of Endurance Events with a Variable Pacing Profile-Time to Embrace the Concept of "Intermittent Endurance Events"?Sports (Basel, Switzerland) · 2024Review
- Acute Oxygen Consumption Response to Fast Start High-Intensity Intermittent Exercise.Sports (Basel, Switzerland) · 2023Article
- Effect of varying recovery intensities on power outputs during severe intensity intervals in trained cyclists during the Covid-19 pandemic.Sport sciences for health · 2023Article
- High-intensity interval training: optimizing oxygen consumption and time to exhaustion taking advantage of the exponential reconstitution behaviour of D'.European journal of applied physiology · 2023Article
- Bi-exponential modelling ofEuropean journal of applied physiology · 2022Article
- The ramp and all-out exercise test to determine critical power: validity and robustness to manipulations in body position.European journal of applied physiology · 2021Article
- The Aerobic and Anaerobic Contribution During Repeated 30-s Sprints in Elite Cyclists.Frontiers in physiology · 2021Article
- Exercise Intensity and Pacing Pattern During a Cross-Country Olympic Mountain Bike Race.Frontiers in physiology · 2021Article
- Physiological and anthropometric determinants of critical power, W' and the reconstitution of W' in trained and untrained male cyclists.European journal of applied physiology · 2020Article
- High-intensity decreasing interval training (HIDIT) increases time above 90%European journal of applied physiology · 2020Article
- The Application of Critical Power, the Work Capacity above Critical Power (W'), and its Reconstitution: A Narrative Review of Current Evidence and Implications for Cycling Training Prescription.Sports (Basel, Switzerland) · 2020Review
- Exercise tolerance during flat over-ground intermittent running: modelling the expenditure and reconstitution kinetics of work done above critical power.European journal of applied physiology · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the responses of intramuscular phosphate-linked metabolites and pH (as assessed by (31)P-MRS) during intermittent high-intensity exercise protocols performed with different recovery-interval durations. Following estimation of the parameters of the power-duration relationship, i.e., the critical power (CP) and curvature constant (W'), for severe-intensity constant-power exercise, nine male subjects completed three intermittent exercise protocols to exhaustion where periods of high-intensity constant-power exercise (60 s) were separated by different durations of passive recovery (18 s, 30 s and 48 s). The tolerable duration of exercise was 304 ± 68 s, 516 ± 142 s, and 847 ± 240 s for the 18-s, 30-s, and 48-s recovery protocols, respectively (P < 0.05). The work done >CP (W>CP) was significantly greater for all intermittent protocols compared with the subjects' W', and this difference became progressively greater as recovery-interval duration was increased. The restoration of intramuscular phosphocreatine concentration during recovery was greatest, intermediate, and least for 48 s, 30 s, and 18 s of recovery, respectively (P < 0.05). The W>CP in excess of W' increased with greater durations of recovery, and this was correlated with the mean magnitude of muscle phosphocreatine reconstitution between work intervals (r = 0.61; P < 0.01). The results of this study show that during intermittent high-intensity exercise, recovery intervals allow intramuscular homeostasis to be restored, with the degree of restoration being related to the duration of the recovery interval. Consequently, and consistent with the intermittent CP model, the ability to perform W>CP during intermittent high-intensity exercise and, therefore, exercise tolerance, increases when recovery-interval duration is extended.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.