Evidence map›Paper›PMID 24067566›Full record

ArticleThe Analyst2013

Simple enrichment and analysis of plasma lysophosphatidic acids.

Jialu Wang, Martha Sibrian-Vazquez, Jorge O Escobedo, Mark Lowry, Lei Wang, Yu-Hsuan Chu, Richard G Moore, Robert M Strongin

Abstract read
In one paragraph

Article in The Analyst, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid.Chemical communications (Cambridge, England) · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jialu WangDepartment of Chemistry, Portland State University, Portland, OR 97201, USA. strongin@pdx.edu.
Martha Sibrian-Vazquez
Jorge O Escobedo
Mark Lowry
Lei Wang
Yu-Hsuan Chu
Richard G Moore
Robert M Strongin

Funding

MBRS IMSD Program at Louisiana State UniversityR25GM069743 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI VICENTE, MARIA DA GRACA HENRIQUES · 2004 to 2017
$3.4M
Development of an Assay for the Early Detection of Ovarian CancerR01CA136491 · NCI · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI MOORE, RICHARD G. · 2009 to 2013
$1.9M
NCI NIH HHS R01 CA136491NCI NIH HHS R01CA136491NIGMS NIH HHS R25 GM069743
6 · The paper itself

Abstract

A simple and highly efficient technique for the analysis of lysophosphatidic acid (LPA) subspecies in human plasma is described. The streamlined sample preparation protocol furnishes the five major LPA subspecies with excellent recoveries. Extensive analysis of the enriched sample reveals only trace levels of other phospholipids. This level of purity not only improves MS analyses, but enables HPLC post-column detection in the visible region with a commercially available fluorescent phospholipids probe. Human plasma samples from different donors were analyzed using the above method and validated by LC-ESI/MS/MS.

Indexed as

Chromatography, High Pressure LiquidHumansLimit of DetectionLysophospholipidsLysophospholipids

Identifiers

PMID24067566
PMCPMC3929374

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.