ReviewVirulence2014
The complex pathogenesis of bacteremia: from antimicrobial clearance mechanisms to the genetic background of the host.
Review in Virulence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Relationship between stress hyperglycaemic ratio (SHR) and critical illness: a systematic review.Cardiovascular diabetology · 2025Pooled it
- Role of cell-free DNA levels in the diagnosis and prognosis of sepsis and bacteremia: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Plasma interleukin-6 concentration for the diagnosis of sepsis in critically ill adults.The Cochrane database of systematic reviews · 2019Pooled it
- Article
- Shapiro Decision Rule, Systemic Inflammatory Response Index, and Systemic Immune-Inflammation Index as Rapid Predictors of Bacteremia in Emergency Department Patients.Infection and drug resistance · 2026Article
- No Evidence of Temperature-Driven Antimicrobial Resistance inAntibiotics (Basel, Switzerland) · 2025Article
- Effects of bacteriophages on gut microbiome functionality.Gut microbes · 2025Review
- Inflammatory response in bacteremia survivors and non-survivors: a case-control study.Scientific reports · 2025Article
- Microbiology and risk factors for bacteremic urinary tract infection: insights from the largest urological center in Pakistan.International urology and nephrology · 2025Article
- Review
- Elizabethkingia meningoseptica: Case report on an emerging pathogen and its associated treatment challenges.IDCases · 2025Article
- Impact of blood culture positivity on clinical outcomes in sepsis: a prospective observational study.Le infezioni in medicina · 2025Article
- Strategies to reduce 28-day mortality in adult patients with bacteremia in the emergency department.BMC infectious diseases · 2024Article
- Disease-associated microbiome signature species in the gut.PNAS nexus · 2024Article
- Tackling salmonellosis: A comprehensive exploration of risks factors, impacts, and solutions.Open veterinary journal · 2024Review
- Culture-independent identification of bloodstream infections from whole blood: prospective evaluation in specimens of known infection status.Journal of clinical microbiology · 2024Article
- Host heterogeneity in humoral bactericidal activity can be complement independent.Frontiers in immunology · 2024Article
- Genetic and immune determinants ofProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Bacteremia in Patients with Sepsis in the ICU: Does It Make a Difference?Microorganisms · 2023Article
- Bacteremia in Severe Mastitis of Dairy Cows.Microorganisms · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteremia develops when bacteria manage to escape the host immune mechanisms or when the otherwise well-orchestrated immune response fails to control bacterial spread due to inherent or acquired immune defects that are associated with susceptibility to infection. The pathogenesis of bacteremia has some characteristic features that are influenced by the genetic signature of the host. In this review, the host defense mechanisms that help prevent bacteremia will be described and the populations who are at risk because of congenital or acquired deficiencies in such mechanisms will be defined. A special mention will be made to novel insights regarding host immune defense against the most commonly isolated organisms from patients with community-acquired bloodstream infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.