Evidence map›Paper›PMID 24067348›Full record

Trial reportJournal of human hypertension2014

Effects of the DASH diet on blood pressure in patients with and without metabolic syndrome: results from the DASH trial.

Fadi Hikmat, L J Appel

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of human hypertension, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Review
  13. Review
  14. What the Latest Evidence Tells Us About Fat and Cardiovascular Health.Diabetes spectrum : a publication of the American Diabetes Association · 2016
    Article
  15. Dietary contributors to hypertension in adults reviewed.Irish journal of medical science · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fadi Hikmat1] Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD, USA [2] Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.ORCID 0000000259951156
L J Appel1] Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD, USA [2] Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA [3] Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

Zoledronic Acid in Treatment of Osteoporosis in PostmenoM01RR002635 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI WILLIAMS, GORDON H · 1985 to 2008
$48.4M
DIETARY PATTERNS AND BLOOD PRESSUREU01HL050968 · NHLBI · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BRAY, GEORGE · 1993 to 1996
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ZIDOVUDINE WITH PROBENECID--EFFECTS OF PROBENECID ON ZIDOVUDINEM01RR000722 · NCRR · JOHNS HOPKINS UNIVERSITY · 1985 to 1996
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DIETARY PATTERNS AND BLOOD PRESSUREU01HL050977 · NHLBI · DUKE UNIVERSITY · PI SVETKEY, LAURA P · 1993 to 1996
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DIETARY PATTERNS AND BLOOD PRESSUREU01HL050981 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI APPEL, LAWRENCE JOHN · 1993 to 1996
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DIETARY PATTERNS AND BLOOD PRESSUREU01HL050982 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI VOLLMER, WILLIAM M · 1993 to 1996
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DIETARY PATTERNS AND BLOOD PRESSUREU01HL050972 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MOORE, THOMAS J · 1993 to 1996
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NCRR NIH HHS RR00722NCRR NIH HHS RR02635NHLBI NIH HHS HL02642NHLBI NIH HHS HL50968NHLBI NIH HHS HL50972NHLBI NIH HHS HL50977NHLBI NIH HHS HL50981NHLBI NIH HHS HL50982
6 · The paper itself

Abstract

In the Dietary Approach to Stop Hypertension (DASH) trial, the DASH diet reduced blood pressure (BP) in a diverse sample of US adults. Subsequent analyses of this trial documented the efficacy of the DASH diet in several subgroups. Although subgroup analyses in individuals with metabolic syndrome (MS) have not been performed, the DASH diet has been recommended in MS patients. This paper is a subgroup analysis of the DASH trial, in which we examined the effect of study diets on BP in participants with and without MS. Participants were stratified according to MS status (99 with MS, 311 without MS (Non-MS)). The trial was a dietary intervention study in which participants were randomized to receive a control diet, a diet rich in fruits and vegetables, or the DASH diet. Outcomes were (i) the difference in BP between the end and the beginning of intervention and (ii) control of hypertension. We found no significant interaction between MS status and diet assignment on BP (each P-interaction >0.05). In the MS subgroup, the DASH diet compared with the control diet reduced systolic BP by 4.9 mm Hg (P=0.006) and diastolic BP by 1.9 mm Hg (P=0.15). In the Non-MS subgroup, corresponding net BP reductions were 5.2 mm Hg (P<0.001) and 2.9 mm Hg (P<0.001), respectively. The DASH diet controlled hypertension in 75% of hypertensive participants with MS (adjusted odds ratio=9.5 vs the control diet, P=0.05). In conclusion, the DASH diet similarly reduces BP in those with and without MS. Our findings provide direct evidence for existing recommendations.

Indexed as

AdultFemaleHumansHypertensionMaleMetabolic SyndromeMiddle AgedTreatment Outcome

Identifiers

PMID24067348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.