Evidence map›Paper›PMID 24067110›Full record

ReviewCognition & emotion2014

Evolutionary mechanisms for loneliness.

John T Cacioppo, Stephanie Cacioppo, Dorret I Boomsma

Abstract readComparative StudyReview
In one paragraph

Review in Cognition & emotion, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 188 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

188 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Neurobiology of loneliness: a systematic review.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Mindfulness training reduces loneliness and increases social contact in a randomized controlled trial.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Trial
  10. Trial
  11. Loneliness in Focus: Proposing a Resident Curriculum.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
    Article
  12. Built Environment and Loneliness Trajectories Among Middle-Aged and Older Adults in China.Journal of urban health : bulletin of the New York Academy of Medicine · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Better Together: Technology-Use Gaps and Loneliness in Older Adults.Behavioral sciences (Basel, Switzerland) · 2026
    Article
  17. Article
  18. Article
  19. Homophily in friendship choice during an early life transition: A cohort network dynamic approach.Evolution and human behavior : official journal of the Human Behavior and Evolution Society · 2026
    Article
  20. Review

128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

John T Cacioppoa Center for Cognitive and Social Neuroscience , University of Chicago , Chicago , IL , USA.
Stephanie Cacioppo
Dorret I Boomsma

Funding

THE SOCIAL ENVIRONMENT, LONELINESS, STRESS AND HEALTHP01AG018911 · NIA · UNIVERSITY OF CHICAGO · PI CACIOPPO, JOHN T. · 2001 to 2007
$8.0M
The Integrative Social Relations, Health and Aging ProjectR01AG034052 · NIA · UNIVERSITY OF CHICAGO · PI CACIOPPO, JOHN T. · 2008 to 2012
$3.8M
Social Regulation of Gene Expression, SupplementR37AG033590 · NIA · UNIVERSITY OF CHICAGO · PI CACIOPPO, JOHN T. · 2010 to 2017
$3.5M
Social Regulation of Gene ExpressionR01AG033590 · NIA · UNIVERSITY OF CHICAGO · PI CACIOPPO, STEPHANIE · 2018 to 2019
$720k
NIA NIH HHS P01 AG018911NIA NIH HHS R01 AG033590NIA NIH HHS R01AG033590NIA NIH HHS R01 AG034052NIA NIH HHS R37 AG033590
6 · The paper itself

Abstract

Robert Weiss (1973) conceptualised loneliness as perceived social isolation, which he described as a gnawing, chronic disease without redeeming features. On the scale of everyday life, it is understandable how something as personally aversive as loneliness could be regarded as a blight on human existence. However, evolutionary time and evolutionary forces operate at such a different scale of organisation than we experience in everyday life that personal experience is not sufficient to understand the role of loneliness in human existence. Research over the past decade suggests a very different view of loneliness than suggested by personal experience, one in which loneliness serves a variety of adaptive functions in specific habitats. We review evidence on the heritability of loneliness and outline an evolutionary theory of loneliness, with an emphasis on its potential adaptive value in an evolutionary timescale.

Indexed as

Biological EvolutionLonelinessAnimalsHumansPsychological Theory

Identifiers

PMID24067110
PMCPMC3855545

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.