ArticleEuropean heart journal. Acute cardiovascular care2012
Prosthetic heart valve obstruction: thrombolysis or surgical treatment?
Article in European heart journal. Acute cardiovascular care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Feasibility and safety of a standardized low-dose thrombolytic therapy for right-sided mechanical prosthetic valve thrombosis in adult congenital heart disease.International journal of cardiology. Congenital heart disease · 2026Article
- Article
- Rapidly progressive obstructive bioprosthetic valve thrombosis after surgical aortic valve replacement: a case report.European heart journal. Case reports · 2025Article
- Thrombosed Mechanical Aortic Valve Treated with Low-Dose Ultraslow Alteplase Infusion.Medicines (Basel, Switzerland) · 2025Article
- Stuck Prosthetic Valves: Clinical Implications of Pannus Formation and Gradient Measurement in Surgical Outcomes.Journal of clinical medicine · 2025Article
- Article
- Mechanical prosthetic valve thrombosis in current era: 5-year follow-up.Indian journal of thoracic and cardiovascular surgery · 2021Article
- Ultraslow thrombolytic therapy in stuck mechanical aortic valve, case report, and review of the literature.Journal of the Saudi Heart Association · 2020Article
- Thrombosis of a biological pulmonary valve in a young patient on anticoagulant therapy with rivaroxaban: a case report.European heart journal. Case reports · 2019Article
- Successful treatment of prosthetic pulmonary valve thrombosis with reteplase: a case report.International medical case reports journal · 2018Article
- A global perspective on mechanical prosthetic heart valve thrombosis: Diagnostic and therapeutic challenges.Anatolian journal of cardiology · 2016Review
- Dysfunction of mechanical heart valve prosthesis: experience with surgical management in 48 patients.Journal of thoracic disease · 2015Article
- Thrombolytic Therapy for Right-Sided Mechanical Pulmonic and Tricuspid Valves: The Largest Survival Analysis to Date.Texas Heart Institute journal · 2015Article
- Treatment of Prosthetic Valve Thrombosis: Current Evidence and Future Directions.Journal of clinical medicine research · 2015Review
- Patient Management with Metallic Valve Prosthesis during Pregnancy and Postpartum Period.Arquivos brasileiros de cardiologia · 2015Article
- Prosthetic mitral valve obstruction: role of real-time three-dimensional transesophageal echocardiography in diagnosis.BMJ case reports · 2015Article
- Systemic thrombolysis: cure for prosthetic mitral valve thrombosis in the comorbid, non-surgical candidate.BMJ case reports · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prosthetic valve thrombosis is a potentially life-threatening complication associated with high morbidity and mortality. Transthorasic and transoesophageal echocardiography play an important role to the diagnosis and provides incremental information about the optimal treatment strategy, while fluoroscopy and cardiac computed tomography may be of added value. Guidelines differ on whether surgical treatment or fibrinolysis should be the treatment of choice for the management of left-sided prosthetic valve thrombosis and these uncertainties underline the need for further prospective randomized controlled trials. Thrombus size, New York Heart Association functional class of the patient, the possible contraindications, the availability of each therapeutic option and the clinician's experience are important determinants for the management of prosthetic valve thrombosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.