ArticleJournal of clinical biochemistry and nutrition2013
Changes of energy metabolism, nutritional status and serum cytokine levels in patients with Crohn's disease after anti-tumor necrosis factor-α therapy.
Article in Journal of clinical biochemistry and nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Clinical study on the screening of biomarkers for Crohn's disease based on blood metabolomics.Frontiers in gastroenterology (Lausanne, Switzerland) · 2026Article
- Review
- [Neutrophil-lymphocyte ratio at 14th week predicts loss of response to 52-week infliximab therapy in patients with Crohn's disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Sarcopenia is a predictive factor for intestinal resection in admitted patients with Crohn's disease.PloS one · 2017Article
- Energy metabolism and nutritional status in hospitalized patients with lung cancer.Journal of clinical biochemistry and nutrition · 2016Article
- Changes in energy metabolism after induction therapy in patients with severe or moderate ulcerative colitis.Journal of clinical biochemistry and nutrition · 2015Article
- Comparison of energy metabolism and nutritional status of hospitalized patients with Crohn's disease and those with ulcerative colitis.Journal of clinical biochemistry and nutrition · 2015Article
- Vitamin D levels in adults with Crohn's disease are responsive to disease activity and treatment.Inflammatory bowel diseases · 2014Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the effects of treatment with antibodies against tumor necrosis factor (TNF)-α on energy metabolism, nutritional status, serum cytokine levels in patients with Crohn's disease (CD). Twelve patients were enrolled. Resting energy expenditure (REE) levels were measured by indirect calorimetry. Crohn's disease activity index (CDAI) significantly decreased after treatment with anti-TNF-α therapy. Anti-TNF-α therapy did not affect REE, but respiratory quotient (RQ) significantly increased after treatment. Serum interleukin-6 levels were significantly decreased and RQ were significantly increased in high REE (≥25 kcal/kg/day) group as compared to low REE (<25 kcal/kg/day) group. In conclusion, high REE value on admission is a predictive factor for good response to treatment with anti-TNF-α antibodies in active CD patients.
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Registered trials
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