ArticleJournal of clinical biochemistry and nutrition2013
Alcohol is an oxidative stressor for gastric epithelial cells: detection of superoxide in living cells.
Article in Journal of clinical biochemistry and nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 59 citations in OpenAlex.
- Lactiplantibacillus plantarum DS1073 protects the gastric mucosa under Helicobacter pylori infection and ethanol stress.Cell communication and signaling : CCS · 2026Article
- Gastroprotective Effects ofInternational journal of molecular sciences · 2026Article
- Gastroprotective Effects of Green Synthesised Silver Nanoparticles Using Artocarpus Lakoocha Leaves Improves Oxidative Stress and Control Inflammation Modulating Via Inflammatory Markers in Ethanol Induced Ulcer Model in Mice.Biological trace element research · 2026Article
- Heme-porphyrin metabolism in photodynamic therapy associated with reactive oxygen species.Journal of clinical biochemistry and nutrition · 2026Article
- Protective effect of short-chain fructo-oligosaccharides from chicory on alcohol-induced injury in GES-1 cells via Keap1/Nrf2 and NLRP3 inflammasome signaling pathways.Frontiers in nutrition · 2024Article
- Effectiveness of natural biomaterials in the protection and healing of experimentally induced gastric mucosa Ulcer in rats.Molecular biology reports · 2023Article
- Silver nanoparticles synthesized from Quercus brantii ameliorated ethanol-induced gastric ulcers in rats by decreasing oxidative stress and improving antioxidant systems.Inflammopharmacology · 2023Article
- Feasibility of mixed herbal medicine for improving gastric function in an alcohol-induced gastritis model.Physical activity and nutrition · 2023Article
- Antioxidant Mechanisms Underlying the Gastroprotective Effect of Menthofuran on Experimentally Induced Gastric Lesions in Rodents.Evidence-based complementary and alternative medicine : eCAM · 2023Article
- Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts.Journal of clinical biochemistry and nutrition · 2023Article
- Chronic alcohol exposure induces hepatocyte damage by inducing oxidative stress, SATB2 and stem cell-like characteristics, and activating lipogenesis.Journal of cellular and molecular medicine · 2022Article
- Evaluation of antioxidant and anti-ulcerogenic effects of Eremurus persicus (Jaub & Spach) Boiss leaf hydroalcoholic extract on ethanol-induced gastric ulcer in rats.Inflammopharmacology · 2021Article
- Modulation of Stem Cell Progeny by Probiotics during Regeneration of Gastric Mucosal Erosions.Biology · 2021Article
- Plasma membrane integrity: implications for health and disease.BMC biology · 2021Review
- Polygonum hydropiper extract attenuates ethanol-induced gastric damage through antioxidant and anti-inflammatory pathways.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021Article
- Preventive Effect of Gonggan (Citrus Reticulata Blanco Var. Gonggan) Peel Extract on Ethanol/HCl-Induced Gastric Injury in MiceFrontiers in pharmacology · 2021Article
- Factors affecting expression and transcription of uncoupling protein 2 gene.The Journal of veterinary medical science · 2020Article
- Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157.Drug design, development and therapy · 2020Article
- Review
- Effectiveness ofOxidative medicine and cellular longevity · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alcohol/ethanol has been reported to derived necrosis and apoptosis with an oxidative stress in gastric mucosal cells. However the clear evidence for reactive oxygen species (ROS) generation by alcohol in gastric cells in vitro is none. In this study, we elucidated ethanol is an oxidative stress inducer on rat gastric epithelial cells by electron paramagnetic resonance measurement in living cells. We also confirmed whether ethanol-induced cellular ROS was derived from mitochondria or not. The results of cellular ROS determination showed that an increment of cellular ROS was shown for 15 min from exposing 1% (v/v) ethanol. Lipid peroxidation in cellular membrane also induced by 1% ethanol and the tendency is same in the results of cellular ROS determination. JC-1 stained showed the decrement of mitochondrial membrane potential. Additionally the localization of cellular ROS coincided with mitochondria. These results indicated that ethanol is not merely a necrotizing factor for gastric epithelial cells, but also an oxidative stress inducer via injured mitochondria.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.