Evidence map›Paper›PMID 24062485›Full record

ArticleThe American journal of tropical medicine and hygiene2013

Detection of Leishmania siamensis DNA in saliva by polymerase chain reaction.

Atchara Phumee, Kanyarat Kraivichian, Sarunyou Chusri, Nopadon Noppakun, Asda Vibhagool, Vivornpun Sanprasert, Vich Tampanya, Henry Wilde, Padet Siriyasatien

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Epidemiology of malaria and leishmaniasis in Thailand (2004-2025): A systematic review.Current research in parasitology & vector-borne diseases · 2026
    Review
  4. Article
  5. Detection ofPathogens (Basel, Switzerland) · 2025
    Article
  6. An update onParasite epidemiology and control · 2024
    Review
  7. Article
  8. Frontiers in public health · 2022
    Review
  9. Genome Assembly and Genome Annotation ofJournal of parasitology research · 2022
    Article
  10. Article
  11. Review
  12. Determination of anti-leishmanial drugs efficacy againstParasite epidemiology and control · 2020
    Article
  13. Detection ofInsects · 2019
    Article
  14. Article
  15. Article
  16. Leishmaniasis in Thailand: A Review of Causative Agents and Situations.The American journal of tropical medicine and hygiene · 2017
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Atchara PhumeeMedical Sciences Program, Department of Parasitology, Division of Dermatology, and Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand; Bumrungrad International Hospital, Bangkok, Thailand; Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand; Excellence Center for Emerging Infectious Diseases, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
Kanyarat Kraivichian
Sarunyou Chusri
Nopadon Noppakun
Asda Vibhagool
Vivornpun Sanprasert
Vich Tampanya
Henry Wilde
Padet Siriyasatien
Chulalongkorn University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymerase chain reaction was used to detect Leishmania siamensis DNA from clinical samples collected from six leishmaniasis patients during 2011-2012. The samples used in this study came from bone marrow, blood, buffy coat, saliva, urine, and tissue biopsy specimens. Saliva was a good source for L. siamensis DNA by polymerase chain reaction. L. siamensis DNA was also found in saliva of an asymptomatic case-patient. Levels of L. siamensis DNA in saliva decreased until being undetectable after treatment. These levels could be used as a marker to evaluate efficacy of the treatment. A larger study is needed to evaluate this method as a screening and survey tool to study the silent background of Leishmania infection among the at-risk population.

Indexed as

AdultAmino Acid SequenceAntiprotozoal AgentsBiomarkersDNA, ProtozoanFemaleHumansLeishmaniaLeishmaniasis, VisceralMaleMiddle AgedMolecular Sequence DataPolymerase Chain ReactionSalivaAntiprotozoal AgentsBiomarkersDNA, Protozoan

Identifiers

PMID24062485
PMCPMC3820333
OpenAlexW2106477955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.