Expanded carrier screening panels-does bigger mean better?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

25 citing papers in PubMed.

1. Assessing clinical education tools for expanded carrier screening.Journal of genetic counseling · 2021
   Trial
2. MLDP-AS: an optimized next-generation sequencing assay for enhanced detection of technically challenging variants in expanded carrier screening.Journal of translational medicine · 2026
   Article
3. Cost-effectiveness of population-based expanded reproductive carrier screening for genetic diseases in Australia: a microsimulation analysis.European journal of human genetics : EJHG · 2025
   Article
4. Clinical application value of pre-pregnancy carrier screening in Chinese Han childbearing population.Molecular genetics & genomic medicine · 2024
   Article
5. Before Is Better: Innovative Multidisciplinary Preconception Care in Different Clinical Contexts.Journal of clinical medicine · 2023
   Review
6. Ethical considerations in gene selection for reproductive carrier screening.Human genetics · 2022
   Review
7. A capillary electrophoresis-based multiplex PCR assay for expanded carrier screening in the eastern Han Chinese population.NPJ genomic medicine · 2022
   Article
8. Clinical Implementation of Expanded Carrier Screening in Pregnant Women at Early Gestational Weeks: A Chinese Cohort Study.Genes · 2021
   Article
9. Current attitudes and preconceptions towards expanded carrier screening in the Eastern Chinese reproductive-aged population.Journal of assisted reproduction and genetics · 2021
   Article
10. Variants ofTherapeutic advances in chronic disease · 2021
    Review
11. Optimizing clinical exome design and parallel gene-testing for recessive genetic conditions in preconception carrier screening: Translational research genomic data from 14,125 exomes.PLoS genetics · 2019
    Article
12. Should Clinicians Leave "Expanded" Carrier Screening Decisions to Patients?AMA journal of ethics · 2019
    Article
13. Commentary: Expanded carrier screening: how much is too much?Genetics in medicine : official journal of the American College of Medical Genetics · 2019
    Article
14. A data-driven evaluation of the size and content of expanded carrier screening panels.Genetics in medicine : official journal of the American College of Medical Genetics · 2019
    Article
15. "A perfect society"- Swedish policymakers' ethical and social views on preconception expanded carrier screening.Journal of community genetics · 2019
    Article
16. The evolving landscape of expanded carrier screening: challenges and opportunities.Genetics in medicine : official journal of the American College of Medical Genetics · 2019
    Review
17. Patient actions and reactions after receiving negative results from expanded carrier screening.Clinical genetics · 2018
    Article
18. Patient perspectives on the use of categories of conditions for decision making about genomic carrier screening results.American journal of medical genetics. Part A · 2018
    Article
19. Structurating Expanded Genetic Carrier Screening: A Longitudinal Analysis of Online News Coverage.Journal of health communication · 2018
    Article
20. Business and Breakthrough: Framing (Expanded) Genetic Carrier Screening for the Public.Health communication · 2017
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

4 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.