ArticleIntensive care medicine2013
Fluid challenge: tracking changes in cardiac output with blood pressure monitoring (invasive or non-invasive).
Article in Intensive care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Fluid challenge in critically ill patients receiving haemodynamic monitoring: a systematic review and comparison of two decades.Critical care (London, England) · 2022Pooled it
- What is the impact of the fluid challenge technique on diagnosis of fluid responsiveness? A systematic review and meta-analysis.Critical care (London, England) · 2017Pooled it
- Physiological changes after fluid bolus therapy in sepsis: a systematic review of contemporary data.Critical care (London, England) · 2014Pooled it
- Trendelenburg maneuver to predict fluid responsiveness in patients under mechanical ventilation with spontaneous breathing: a prospective study.BMC anesthesiology · 2026Article
- Easy method to determine fluid responsiveness in septic shock patients: end-tidal CO2 - a prospective observational study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024Observational
- Pathophysiology of fluid administration in critically ill patients.Intensive care medicine experimental · 2022Review
- Can passive leg raise predict the response to fluid resuscitation in ED?BMC emergency medicine · 2022Article
- The ability of pulse oximetry-derived peripheral perfusion index to detect fluid responsiveness in patients with septic shock.Journal of anesthesia · 2021Article
- Arterial Load and Norepinephrine Are Associated With the Response of the Cardiovascular System to Fluid Expansion.Frontiers in physiology · 2021Article
- Fluid administration for acute circulatory dysfunction using basic monitoring.Annals of translational medicine · 2020Review
- Evaluation of radial artery pulse pressure effects on detection of stroke volume changes after volume loading maneuvers in cardiac surgical patients.Annals of translational medicine · 2020Article
- How to detect a positive response to a fluid bolus when cardiac output is not measured?Annals of intensive care · 2019Article
- Effect of hypotensive hypovolemia and thoracic epidural anesthesia on plasma pro-atrial natriuretic peptide to indicate deviations in central blood volume in pigs: a blinded, randomized controlled trial.Local and regional anesthesia · 2019Article
- Fluid administration for acute circulatory dysfunction using basic monitoring: narrative review and expert panel recommendations from an ESICM task force.Intensive care medicine · 2019Article
- Respiratory changes of the inferior vena cava diameter predict fluid responsiveness in spontaneously breathing patients with cardiac arrhythmias.Annals of intensive care · 2018Article
- Passive Leg Raising in Intensive Care Medicine.Chinese medical journal · 2016Review
- Effects of fluid administration on arterial load in septic shock patients.Intensive care medicine · 2015Article
- New tools for optimizing fluid resuscitation in acute pancreatitis.World journal of gastroenterology · 2014Review
- Dynamic arterial elastance as a predictor of arterial pressure response to fluid administration: a validation study.Critical care (London, England) · 2014Observational
- Functional haemodynamic monitoring.Current opinion in critical care · 2014Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess whether invasive and non-invasive blood pressure (BP) monitoring allows the identification of patients who have responded to a fluid challenge, i.e., who have increased their cardiac output (CO).
methodsPatients with signs of circulatory failure were prospectively included. Before and after a fluid challenge, CO and the mean of four intra-arterial and oscillometric brachial cuff BP measurements were collected. Fluid responsiveness was defined by an increase in CO ≥10 or ≥15% in case of regular rhythm or arrhythmia, respectively.
resultsIn 130 patients, the correlation between a fluid-induced increase in pulse pressure (Δ500mlPP) and fluid-induced increase in CO was weak and was similar for invasive and non-invasive measurements of BP: r² = 0.31 and r² = 0.29, respectively (both p < 0.001). For the identification of responders, invasive Δ500mlPP was associated with an area under the receiver-operating curve (AUC) of 0.82 (0.74-0.88), similar (p = 0.80) to that of non-invasive Δ500mlPP [AUC of 0.81 (0.73-0.87)]. Outside large gray zones of inconclusive values (5-23% for invasive Δ500mlPP and 4-35% for non-invasive Δ500mlPP, involving 35 and 48% of patients, respectively), the detection of responsiveness or unresponsiveness to fluid was reliable. Cardiac arrhythmia did not impair the performance of invasive or non-invasive Δ500mlPP. Other BP-derived indices did not outperform Δ500mlPP.
conclusionsAs evidenced by large gray zones, BP-derived indices poorly reflected fluid responsiveness. However, in our deeply sedated population, a high increase in invasive pulse pressure (>23%) or even in non-invasive pulse pressure (>35%) reliably detected a response to fluid. In the absence of a marked increase in pulse pressure (<4-5%), a response to fluid was unlikely.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.