Evidence map›Paper›PMID 24061608›Full record

ReviewEuropean archives of psychiatry and clinical neuroscience2013

Modulating neural plasticity with non-invasive brain stimulation in schizophrenia.

Alkomiet Hasan, Thomas Wobrock, Tarek Rajji, Berend Malchow, Zafiris J Daskalakis

Abstract readReview
PubMed Publisher
In one paragraph

Review in European archives of psychiatry and clinical neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. A meta-analysis of the effects of aging on motor cortex neurophysiology assessed by transcranial magnetic stimulation.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2016
    Pooled it
  2. Trial
  3. A Novel Therapeutic Mechanism for Nicotine Craving in Schizophrenia.medRxiv : the preprint server for health sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Smoking restores impaired LTD-like plasticity in schizophrenia: a transcranial direct current stimulation study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015
    Article
  12. Article
  13. Therapeutic targets in major psychiatric disorders revisited.European archives of psychiatry and clinical neuroscience · 2013
    Article
  14. Transcranial direct current stimulation in schizophrenia.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Alkomiet HasanDeparment of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Nussbaumstr 7, 80336, Munich, Germany, alkomiet.hasan@med.uni-muenchen.de.
Thomas Wobrock
Tarek Rajji
Berend Malchow
Zafiris J Daskalakis
Centre for Addiction and Mental Health · CALudwig-Maximilians-Universität München · DEKlinikum Darmstadt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia is a severe mental disorder characterised by a complex phenotype including positive, negative, affective and cognitive symptoms. Various theories have been developed to integrate the clinical phenotype into a strong neurobiological framework. One theory describes schizophrenia as a disorder of impaired neural plasticity. Recently, non-invasive brain stimulation techniques have garnered much attention to their ability to modulate plasticity and treat schizophrenia. The aim of this review is to introduce the basic physiological principles of conventional non-invasive brain stimulation techniques and to review the available evidence for schizophrenia. Despite promising evidence for efficacy in a large number of clinical trials, we continue to have a rudimentary understanding of the underlying neurobiology. Additional investigation is required to improve the response rates to non-invasive brain stimulation, to reduce the interindividual variability and to improve the understanding of non-invasive brain stimulation in schizophrenia.

Indexed as

Deep Brain StimulationHumansNeuronal PlasticitySchizophrenia

Identifiers

PMID24061608
OpenAlexW1980292298

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.