Evidence map›Paper›PMID 24060569›Full record

ArticleVaccine2013

Cost-effectiveness of rotavirus vaccination programs in Taiwan.

Wan-Chi Chang, Catherine Yen, Cheng-Liang Chi, Fang-Tzy Wu, Yhu-Chering Huang, Jen-Shiou Lin, Fu-Chen Huang, Jacqueline E Tate, Ho-Sheng Wu, Chao A Hsiung

Open access · greenAbstract read
In one paragraph

Article in Vaccine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Systematic review of the economic value of diarrheal vaccines.Human vaccines & immunotherapeutics · 2014
    Pooled it
  2. Observational
  3. Article
  4. Economics and financing of vaccines for diarrheal diseases.Human vaccines & immunotherapeutics · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Wan-Chi ChangDivision of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Catherine Yen
Cheng-Liang Chi
Fang-Tzy Wu
Yhu-Chering Huang
Jen-Shiou Lin
Fu-Chen Huang
Jacqueline E Tate
Ho-Sheng Wu
Chao A Hsiung
National Health Research Institutes · TWCenters for Disease Control and Prevention · USCenter for Disease Control · TWChanghua Christian Hospital · TWKaohsiung Chang Gung Memorial Hospital · TWLinkou Chang Gung Memorial Hospital · TWMinistry of Health and Welfare · TW

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundIn Taiwan, two rotavirus vaccines are available on the private market, but are not included in the National Immunization Program (NIP). To help assess whether to include rotavirus vaccines in the NIP, we examined the potential impact and cost-effectiveness of vaccination, from the health care system perspective alone.

methodsWe used a Microsoft Excel-based model to assess rotavirus vaccination impact on rotavirus disease burden and the cost-effectiveness of 2-dose and 3-dose vaccination programs among a birth cohort of Taiwanese children followed for 5 years. Principal model inputs included data on rotavirus disease burden and related healthcare costs, vaccination cost and coverage rates, and vaccine efficacy. Principal model outputs included the number of health-related events and costs averted and incremental cost per disability-adjusted life year averted.

resultsA national rotavirus vaccination program, regardless of number of doses per course, would prevent 4 deaths, >10,500 hospitalizations, and >64,000 outpatient visits due to rotavirus infection among children <5 years annually, resulting in ~80%, 90%, and 70% declines in these outcomes, respectively, and a ~$7 million decline in annual medical costs. A national 2- or 3-dose vaccination program would be cost-saving up to $13.30/dose ($26.60/course) or $7.98/dose ($23.94/course), respectively; very cost-effective up to $24.08 per dose ($48.16/course) or $15.18/dose ($45.54/course), respectively; and cost-effective up to $45.65/dose ($91.30/course) or $29.59/dose ($88.77/course), respectively.

conclusionsA national rotavirus vaccination program could substantially reduce rotavirus disease burden among Taiwanese children and be potentially cost-effective, depending on the vaccine price.

Indexed as

Child, PreschoolCost-Benefit AnalysisFemaleGastroenteritisHumansInfantInfant, NewbornMaleModels, StatisticalRotavirus InfectionsRotavirus VaccinesTaiwanVaccinationRotavirus VaccinesCost-effectivenessGastroenteritisRotavirusRotavirus vaccine

Identifiers

PMID24060569
PMCPMC11984656
OpenAlexW2017616753

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.