Evidence map›Paper›PMID 24060008›Full record

ArticleACS nano2013

Dynamical treatment of charge transfer through duplex nucleic acids containing modified adenines.

Giorgia Brancolini, Agostino Migliore, Stefano Corni, Miguel Fuentes-Cabrera, F Javier Luque, Rosa Di Felice

Abstract read
In one paragraph

Article in ACS nano, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Conformational gating of DNA conductance.Nature communications · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Giorgia BrancoliniCNR Institute of Nanoscience , S3 Center, Via Campi 213/A, 41125 Modena, Italy.
Agostino Migliore
Stefano Corni
Miguel Fuentes-Cabrera
F Javier Luque
Rosa Di Felice
Istituto Nanoscienze · ITOak Ridge National Laboratory · USTel Aviv University · ILUniversitat de Barcelona · ESUniversity of Southern California · US

Funding

Charge-Transfer Dynamics Relevant to Protein-Mediated Energy TransductionR01GM071628 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI THERIEN, MICHAEL J · 2004 to 2014
$2.3M
European Research Council 226628NIGMS NIH HHS GM071628NIGMS NIH HHS R01 GM071628
6 · The paper itself

Abstract

We address the issue of whether chemical alterations of nucleobases are an effective tool to modulate charge transfer through DNA molecules. Our investigation uses a multilevel computational approach based on classical molecular dynamics and quantum chemistry. We find yet another piece of evidence that structural fluctuations are a key factor to determine the electronic structure of double-stranded DNA. We argue that the electronic structure and charge transfer ability of flexible polymers is the result of a complex intertwining of various structural, dynamical and chemical factors. Chemical intuition may be used to design molecular wires, but this is not the sole component in the complex charge transfer mechanism through DNA.

Indexed as

AdenineDNAHydrogen BondingMolecular Dynamics SimulationQuantum TheoryAdenineDNA

Identifiers

PMID24060008
PMCPMC3903158
OpenAlexW2010723069

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.