Evidence map›Paper›PMID 24059819›Full record

ArticleDevelopment and psychopathology2014

Mother-infant attachment and the intergenerational transmission of posttraumatic stress disorder.

Michelle Bosquet Enlow, Byron Egeland, Elizabeth Carlson, Emily Blood, Rosalind J Wright

Abstract read
In one paragraph

Article in Development and psychopathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. A Pilot Study of a Trauma-Informed Skills Parenting Group.Journal of child & adolescent trauma · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Mothers' psychopathology and their adult offspring's cortisol level in a Rwandan sample.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Does Hope Reverberate Between Generations?Qualitative health research · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michelle Bosquet EnlowBoston Children's Hospital.
Byron EgelandUniversity of Minnesota.
Elizabeth CarlsonUniversity of Minnesota.
Emily BloodBoston Children's Hospital.
Rosalind J WrightHarvard Medical School.

Funding

Stress, Environment, and Genetics in Urban AsthmaR01HL080674 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2005 to 2014
$7.0M
ADAPTATION IN A RISK SAMPLE--INFANCY TO EARLY ADULTHOODR01MH040864 · NIMH · UNIVERSITY OF MINNESOTA TWIN CITIES · PI EGELAND, BYRON R · 1986 to 2005
$3.6M
MULTI-LEVEL ANALYSIS OF URBAN CHILDHOOD ASTHMA RISKR01ES010932 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2000 to 2004
$3.0M
The Development Construction of Adult CompetenceR01HD054850 · NICHD · UNIVERSITY OF MINNESOTA · PI COLLINS, WILLARD ANDREW · 2007 to 2011
$2.8M
Air pollution, stress and urban child developmentR01MD006086 · NIMHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2010 to 2014
$2.2M
Asthma Coalition on Community, Environment and StressU01HL072494 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2002 to 2003
$1.5M
Reactivity and Regulation in the Intergenerational Transmission of PTSDK08MH074588 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI BOSQUET ENLOW, MICHELLE A · 2007 to 2011
$744k
NHLBI NIH HHS R01 HL080674NHLBI NIH HHS R01HL080674NHLBI NIH HHS U01 HL072494NHLBI NIH HHS U01HL072494NICHD NIH HHS R01HD054850NIEHS NIH HHS R01 ES010932NIEHS NIH HHS R01ES010932NIMHD NIH HHS R01 MD006086NIMHD NIH HHS R01MD006086NIMH NIH HHS K08 MH074588NIMH NIH HHS K08MH074588NIMH NIH HHS R01 MH040864
6 · The paper itself

Abstract

Evidence for the intergenerational transmission of posttraumatic stress disorder (PTSD) is documented in the literature, although the underlying mechanisms are poorly understood. Attachment theory provides a framework for elucidating the ways in which maternal PTSD may increase offspring PTSD vulnerability. The current study utilized two independent prospective data sets to test the hypotheses that (a) maternal PTSD increases the probability of developing an insecure mother-infant attachment relationship and (b) an insecure mother-infant attachment relationship increases the risk of developing PTSD following trauma exposure in later life. In the first study of urban, primarily low-income ethnic/racial minority mothers and infants (N = 45 dyads), elevated maternal PTSD symptoms at 6 months were associated with increased risk for an insecure, particularly disorganized, mother-infant attachment relationship at 13 months. In the second birth cohort of urban, low-income mothers and children (N = 96 dyads), insecure (avoidant or resistant) attachment in infancy was associated in a dose-response manner with increased lifetime risk for a diagnosis of PTSD by adolescence. A history of disorganized attachment in infancy predicted severity of PTSD symptoms, including reexperiencing, avoidance, hyperarousal, and total symptoms, at 17.5 years. In both studies, associations between attachment and PTSD were not attributable to numerous co-occurring risk factors. The findings suggest that promoting positive mother-child relationships in early development, particularly in populations at high risk for trauma exposure, may reduce the incidence of PTSD.

Indexed as

Mother-Child RelationsObject AttachmentAdolescentAdultChild of Impaired ParentsFemaleHumansInfantMaleMothersProspective StudiesRisk FactorsStress Disorders, Post-TraumaticYoung Adult

Identifiers

PMID24059819
PMCPMC4145695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.