Evidence map›Paper›PMID 24058825›Full record

ArticleWorm2012

How worms survive desiccation: Trehalose pro water.

Cihan Erkut, Sider Penkov, Karim Fahmy, Teymuras V Kurzchalia

Open access · bronzeAbstract read
In one paragraph

Article in Worm, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. eLife · 2017
    Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Cihan ErkutMax Planck Institute of Molecular Cell Biology and Genetics; Dresden, Germany.
Sider Penkov
Karim Fahmy
Teymuras V Kurzchalia
Max Planck Institute of Molecular Cell Biology and Genetics · DEHelmholtz-Zentrum Dresden-Rossendorf · DEInstitute of Genetics · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While life requires water, many organisms, known as anhydrobiotes, can survive in the absence of water for extended periods of time. Although discovered 300 years ago, we know very little about the fascinating phenomenon of anhydrobiosis. In this paper, we summarize our previous findings on the desiccation tolerance of the Caenorhabditis elegans dauer larva. A special emphasis is given to the role of trehalose in protecting membranes against desiccation. We also propose a simple mechanism for this process.

Indexed as

anhydrobiosisCaenorhabditis elegansdauerdesiccationmembrane packingmembrane phase transitionmembrane protectionmetabolic depressiontrehalose

Identifiers

PMID24058825
PMCPMC3670174
OpenAlexW2022272883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.