Trial reportPloS one2013
Ambient air toxics and asthma prevalence among a representative sample of US kindergarten-age children.
Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Geographical Differences of Risk of Asthma and Allergic Rhinitis according to Urban/Rural Area: a Systematic Review and Meta-analysis of Cohort Studies.Journal of urban health : bulletin of the New York Academy of Medicine · 2023Pooled it
- Urban Lifestyle and Climate-Driven Environmental Exposures: Immunological Consequences for Pediatric Respiratory Allergies.Immunity, inflammation and disease · 2025Review
- Environmental Inequality in Estimated Cancer Risk from Airborne Toxic Exposure across United States Communities from 2011 to 2019.Environmental science & technology · 2024Article
- Inequalities in Environmental Cancer Risk and Carcinogen Exposures: A Scoping Review.International journal of environmental research and public health · 2023Article
- Health Outcomes in Children Associated with Prenatal and Early-Life Exposures to Air Pollution: A Narrative Review.Toxics · 2022Review
- Inequalities in Exposure to Ambient Air Neurotoxicants and Disparities in Markers of Neurodevelopment in Children by Maternal Nativity Status.International journal of environmental research and public health · 2021Article
- Excess free fructose, apple juice, high fructose corn syrup and childhood asthma risk - the National Children's Study.Nutrition journal · 2020Article
- Combined association of BTEX and material hardship on ADHD-suggestive behaviours among a nationally representative sample of US children.Paediatric and perinatal epidemiology · 2019Article
- Article
- Environmental styrene exposure and neurologic symptoms in U.S. Gulf coast residents.Environment international · 2018Article
- Maternal Obesity, Gestational Weight Gain, and Asthma in Offspring.Preventing chronic disease · 2017Article
- Using machine learning to identify air pollution exposure profiles associated with early cognitive skills among U.S. children.Environmental pollution (Barking, Essex : 1987) · 2017Article
- The Combined Influence of Air Pollution and Home Learning Environment on Early Cognitive Skills in Children.International journal of environmental research and public health · 2017Article
- Prevalence and Occupational and Environmental Risk Factors of Self-Reported Asthma: Evidence from a Cross-Sectional Survey in Seven Chinese Cities.International journal of environmental research and public health · 2016Article
- Asthma exacerbations and traffic: examining relationships using link-based traffic metrics and a comprehensive patient database.Environmental health : a global access science source · 2016Article
- Short-term association between particular matter air pollution and pediatric clinical visits for wheezing in a subarea of Shanghai.Environmental science and pollution research international · 2016Article
- Effects of air pollution on human health and practical measures for prevention in Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016Review
- Acrolein and asthma attack prevalence in a representative sample of the United States adult population 2000-2009.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCriteria pollutants have been associated with exacerbation of children's asthma, but the role of air toxics in relation to asthma is less clear. Our objective was to evaluate whether exposure to outdoor air toxics in early childhood increased asthma risk or severity.
methodsAir toxics exposure was estimated using the 2002 National Air toxics Assessment (NATA) and linked to longitudinal data (n=6950) from a representative sample of US children born in 2001 and followed through kindergarten-age in the Early Child Longitudinal Study-Birth Cohort (ECLS-B).
resultsOverall, 17.7% of 5.5 year-olds had ever been told by a healthcare professional they had asthma, and 6.8% had been hospitalized or visited an emergency room for an asthma attack. Higher rates of asthma were observed among boys (20.1%), low-income (24.8%), and non-Hispanic black children (30.0%) (p≤0.05). Air toxics exposure was greater for minority race/ethnicity (p<0.0001), low income (p<0.0001), non-rural area (p<0.001). Across all analyses, greater air toxics exposure, as represented by total NATA respiratory hazard index, or when limited to respiratory hazard index from onroad mobile sources or diesel PM, was not associated with a greater prevalence of asthma or hospitalizations (p trend >0.05). In adjusted logistic regression models, children exposed to the highest respiratory hazard index were not more likely to have asthma compared to those exposed to the lowest respiratory hazard index of total, onroad sources, or diesel PM.
conclusionsEarly childhood exposure to outdoor air toxics in a national sample has not previously been studied relative to children's asthma. Within the constraints of the study, we found no evidence that early childhood exposure to outdoor air toxics increased risk for asthma. As has been previously reported, it is evident that there are environmental justice and disparity concerns for exposure to air toxics and asthma prevalence in US children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.