ArticlePloS one2013
Vitellogenin from the silkworm, Bombyx mori: an effective anti-bacterial agent.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
- Unveiling the conserved mechanism of microsporidian vertical transmission: A comparative study ofVirulence · 2026Article
- Wavelength-Specific Transcriptomic Responses ofInsects · 2026Article
- Dual functions of the Aedes aegypti ecdysone receptor in dengue virus replication and reproduction control.Parasites & vectors · 2026Article
- Review
- Unusual functions of insect vitellogenins: minireview.Physiological research · 2023Review
- Article
- Article
- Interaction of Liberibacter Solanacearum with Host Psyllid Vitellogenin and Its Association with Autophagy.Microbiology spectrum · 2022Article
- Global Profiling of Genes Expressed in the Silk Glands of Philippine-Reared Mulberry SilkwormsInsects · 2022Article
- Differential Expression of Major Royal Jelly Proteins in the Hypopharyngeal Glands of the HoneybeeInsects · 2022Article
- Article
- Article
- Deciphering the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor.PLoS pathogens · 2020Article
- JNK signaling pathway regulates the development of ovaries and synthesis of vitellogenin (Vg) in the swimming crab Portunus trituberculatus.Cell stress & chaperones · 2020Article
- Molecular characterization of clathrin heavy chain (Chc) in Rhipicephalus haemaphysaloides and its effect on vitellogenin (Vg) expression via the clathrin-mediated endocytic pathway.Experimental & applied acarology · 2020Article
- Immune Defenses of a Beneficial Pest: The Mealworm Beetle,Frontiers in physiology · 2019Review
- CRISPR/Cas9-Mediated Vitellogenin Receptor Knockout Leads to Functional Deficiency in the Reproductive Development ofFrontiers in physiology · 2019Article
- Trans-generational Immune Priming in Invertebrates: Current Knowledge and Future Prospects.Frontiers in immunology · 2019Review
- Vitellogenin knockdown strongly affects cotton boll weevil egg viability but not the number of eggs laid by females.Meta gene · 2016Article
- The Essential Role of Vitellogenin Receptor in Ovary Development and Vitellogenin Uptake in Bactrocera dorsalis (Hendel).International journal of molecular sciences · 2015Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silkworm, Bombyx mori, vitellogenin (Vg) was isolated from perivisceral fat body of day 3 of pupa. Both Vg subunits were co-purified as verified by mass spectrometry and immunoblot. Purified Vg responded to specific tests for major posttranslational modifications on native gels indicating its nature as lipo-glyco-phosphoprotein. The Vg fraction had strong antibacterial activity against Gram negative bacterium Escherichia coli and Gram positive bacterium Bacillus subtilis. Microscopic images showed binding of Vg to bacterial cells and their destruction. When infected silkworm larvae were treated with purified Vg they survived the full life cycle in contrast to untreated animals. This result showed that Vg has the ability to inhibit the proliferation of bacteria in the silkworm fluid system without disturbing the regular metabolism of the host.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.