ArticleAdvanced functional materials2013
Slowly degradable porous silk microfabricated scaffolds for vascularized tissue formation.
Article in Advanced functional materials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 64 citations in OpenAlex.
- Janus decellularized membrane with anisotropic cell guidance and anti-adhesion silk-based coatings for spinal dural repair.Nature communications · 2025Article
- On-Chip Reconstitution of Uniformly Shear-Sensing 3D Matrix-embedded Multicellular Blood Microvessel.Advanced functional materials · 2024Article
- Elimination of Induced Hypoxic Regions in Depth of 3D Porous Silk Scaffolds by the Introduction of Channel Configuration.BioMed research international · 2022Article
- Stimuli-responsive hydrogels for manipulation of cell microenvironment: From chemistry to biofabrication technology.Progress in polymer science · 2019Article
- Current advances for bone regeneration based on tissue engineering strategies.Frontiers of medicine · 2019Review
- 3D Printing of Lotus Root-Like Biomimetic Materials for Cell Delivery and Tissue Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2017Article
- Modular flow chamber for engineering bone marrow architecture and function.Biomaterials · 2017Article
- Simulation of ECM with Silk and Chitosan Nanocomposite Materials.Journal of materials chemistry. B · 2017Article
- Stem cell-derived vasculature: A potent and multidimensional technology for basic research, disease modeling, and tissue engineering.Biochemical and biophysical research communications · 2016Review
- LumeNEXT: A Practical Method to Pattern Luminal Structures in ECM Gels.Advanced healthcare materials · 2016Article
- Silk Biomaterials with Vascularization Capacity.Advanced functional materials · 2016Article
- In vivo bioresponses to silk proteins.Biomaterials · 2015Review
- Control of silicification by genetically engineered fusion proteins: silk-silica binding peptides.Acta biomaterialia · 2015Article
- A mild process to design silk scaffolds with reduced β-sheet structure and various topographies at the nanometer scale.Acta biomaterialia · 2015Article
- Hydrogel bioprinted microchannel networks for vascularization of tissue engineering constructs.Lab on a chip · 2014Article
- The effect of scaffold macroporosity on angiogenesis and cell survival in tissue-engineered smooth muscle.Biomaterials · 2014Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
There is critical clinical demand for tissue-engineered (TE), three-dimensional (3D) constructs for tissue repair and organ replacements. Current efforts toward this goal are prone to necrosis at the core of larger constructs because of limited oxygen and nutrient diffusion. Therefore, critically sized 3D TE constructs demand an immediate vascular system for sustained tissue function upon implantation. To address this challenge the goal of this project was to develop a strategy to incorporate microchannels into a porous silk TE scaffold that could be fabricated reproducibly using microfabrication and soft lithography. Silk is a suitable biopolymer material for this application because it is mechanically robust, biocompatible, slowly degrades
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.