ReviewThe Yale journal of biology and medicine2013
Parental permission and child assent in research on children.
Review in The Yale journal of biology and medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Use of Waivers of Guardian Permission in the United States for Pediatric Digital Health Intervention Research Since 2020: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Systematic Review: Effect of Health Education Intervention on Improving Knowledge, Attitudes and Practices of Adolescents on Malnutrition.Nutrients · 2020Pooled it
- Improved parental understanding by an enhanced informed consent form: a randomized controlled study nested in a paediatric drug trial.BMJ open · 2019Trial
- Effective Community Consultation for Prehospital EFIC Research: Lessons from a 20-Site Pediatric Trial.Prehospital emergency care · 2026Article
- Caregiver decision-making on pediatric research participation in congenital heart disease in western China: a qualitative study.Frontiers in public health · 2026Article
- Honoring childhood agency in developmental research: Best practices, applications, and insights.Methods in Psychology (Online) · 2025Article
- Qualitative study on ethics in paediatric Systemic Inflammatory Response Syndrome (SIRS) research: perspectives of Turkish legal guardians.BMC medical ethics · 2025Article
- Base and Prime Editing for Inherited Retinal Diseases: Delivery Platforms, Safety, Efficacy, and Translational Perspectives.Pharmaceutics · 2025Review
- Digital Storytelling to Reduce Hispanic Parents' COVID-19 Vaccine Hesitancy: A Pilot Randomized Controlled Trial.Vaccines · 2025Article
- Article
- Tailoring Sexual Health Research Practices to Meet the Needs of Adolescent Girls in Low- and Middle-Income Countries: Findings from Mexico.Adolescents (Basel, Switzerland) · 2024Article
- Article
- Children and bioethics: clarifying consent and assent in medical and research settings.British medical bulletin · 2023Review
- Co-creation of information materials within the assent process: From theory to practice.Health expectations : an international journal of public participation in health care and health policy · 2023Article
- What information and the extent of information to be provided in an informed assent/consent form of pediatric drug trials.BMC medical ethics · 2022Article
- Ethical challenges in consent procedures involving pediatric cancer patients in Saudi Arabia: An exploratory survey.Developing world bioethics · 2022Article
- Children's Understanding of Informed Assents in Research Studies.Healthcare (Basel, Switzerland) · 2021Article
- Understanding the child-doctor relationship in research participation: a qualitative study.BMC pediatrics · 2020Article
- The Importance of Engaging Children in Research Decision-Making: A Preliminary Mixed-Methods Study.Ethics & human research · 2020Article
- Assent and consent in adolescent research: teachers' perspectives from a developing country.Heliyon · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Grounded on the ethical principle of respect for persons, parental permission and child assent function together to protect the child and to foster the development of the child's self-determination. Although both parental permission and child assent involve the same components of information sharing, comprehension, and voluntariness, how these three components are understood and operationalized should differ depending on the developmental level of the child. For example, the amount of information that a child must comprehend to provide meaningful and developmentally appropriate child assent (or dissent) should be allowed to vary with the age and maturity of the child. By understanding child assent together with the important protections of parental permission, child assent does not need to be burdened with the same informational and process requirements. As a result, the age (as a proxy for developmental stage) at which a child is deemed capable of assent would be lower (i.e., 5 to 7 years old). By assuming a lack of capacity, the potential arises to dishonor and disregard a child's wishes by failing to solicit meaningful assent or dissent. Further research needs to be done on how best to obtain truly informed and voluntary parental permission and child assent for research participation.
Indexed as
Identifiers
24058304PMC3767214What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.