SynthesisCurrent atherosclerosis reports2013
Iron deficiency and cardiovascular disease: an updated review of the evidence.
Synthesis in Current atherosclerosis reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Hydroxytyrosol supplementation increases vitamin C levels in vivo. A human volunteer trial.Redox biology · 2017Trial
- Association between latent profile of dietary intake and cardiovascular diseases (CVDs): Results from Fasa Adults Cohort Study (FACS).Scientific reports · 2023Article
- The effect of circulating iron on barrier integrity of primary human endothelial cells.Scientific reports · 2023Article
- Article
- The role of iron metabolism in chronic diseases related to obesity.Molecular medicine (Cambridge, Mass.) · 2022Review
- Association between iron status and incident coronary artery disease: a population based-cohort study.Scientific reports · 2022Article
- Herceptin induces ferroptosis and mitochondrial dysfunction in H9c2 cells.International journal of molecular medicine · 2022Article
- Increased Serum Soluble Transferrin Receptor Levels Were Associated With High Prevalence of Cardiovascular Diseases: Insights From the National Health and Nutrition Examination Survey 2017-2018.Frontiers in cell and developmental biology · 2022Article
- Article
- Certain Associations Between Iron Biomarkers and Total and γ' Fibrinogen and Plasma Clot Properties Are Mediated by Fibrinogen Genotypes.Frontiers in nutrition · 2021Article
- Validation of a food frequency questionnaire as a tool for assessing dietary intake in cardiovascular disease research and surveillance in Bangladesh.Nutrition journal · 2020Article
- Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment.Current cardiology reports · 2020Review
- Transferrin plays a central role in coagulation balance by interacting with clotting factors.Cell research · 2020Article
- Maternal cadmium exposure in the mouse leads to increased heart weight at birth and programs susceptibility to hypertension in adulthood.Scientific reports · 2019Article
- Ferritin in Kidney and Vascular Related Diseases: Novel Roles for an Old Player.Pharmaceuticals (Basel, Switzerland) · 2019Review
- Iron induces insulin resistance in cardiomyocytes via regulation of oxidative stress.Scientific reports · 2019Article
- Ferritin levels throughout childhood and metabolic syndrome in adolescent stage.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2019Article
- The Effects of Dietary Polyphenols on Circulating Cardiovascular Disease Biomarkers and Iron Status: A Systematic Review.Nutrition and metabolic insights · 2019Review
- More evidence is needed. Iron, incident cognitive decline and dementia: a systematic review.Therapeutic advances in chronic disease · 2018Review
- The role of micronutrients in the response to ambient air pollutants: Potential mechanisms and suggestions for research design.Journal of toxicology and environmental health. Part B, Critical reviews · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Body iron status has been suggested to be related to the development of cardiovascular disease (CVD). Biologically plausible mechanisms for this association have been described, however epidemiological studies on iron status and CVD risk have provided conflicting results. The lack of consistency is likely explained by differences in the study design, the measures used for the assessment of iron status, the definition of outcomes, and adjustment for confounders. To help clarify the available evidence, we report a systematic review of published cross-sectional, longitudinal, and intervention studies evaluating the relationship between different measures of iron status and CVD risk. The most likely scenario that emerges from the available studies is that, in the reference range, iron status has a neutral effect. Extreme conditions of iron deficiency, as well as of iron overload, are associated with modestly increased CVD risk, although with different proposed mechanisms.
Indexed as
Identifiers
24057693What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.