ArticleExperimental & applied acarology2014
Cellular responses to Rhipicephalus microplus infestations in pre-sensitised cattle with differing phenotypes of infestation.
Article in Experimental & applied acarology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- Comprehensive evaluation of tick infestation dynamics and host response in Kankrej and Holstein Friesian crossbred cattle.Veterinary and animal science · 2026Article
- Transcriptional changes in the peripheral blood leukocytes from Brangus cattle before and after tick challenge with Rhipicephalus australis.BMC genomics · 2022Article
- A genetic and immunological comparison of tick-resistance in beef cattle following artificial infestation with Rhipicephalus ticks.Experimental & applied acarology · 2020Article
- Changes in biochemical proxy indicators for nutritional stress resilience from Boran and Nguni cows reared in dry arid rangeland.Tropical animal health and production · 2017Article
- Cellular response in the tick feeding site in crossbred cattle artificially infested by Rhipicephalus microplus.Experimental & applied acarology · 2017Article
- Conservation of indigenous cattle genetic resources in Southern Africa's smallholder areas: turning threats into opportunities - A review.Asian-Australasian journal of animal sciences · 2017Review
- Bovine Immune Factors Underlying Tick Resistance: Integration and Future Directions.Frontiers in cellular and infection microbiology · 2017Review
- Cattle TickFrontiers in cellular and infection microbiology · 2017Review
- Genetic diversity in South African Nguni cattle ecotypes based on microsatellite markers.Tropical animal health and production · 2016Article
- Modulation of host immunity by tick saliva.Journal of proteomics · 2015Review
- Are ticks venomous animals?Frontiers in zoology · 2014Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The blue tick, Rhipicephalus microplus, threatens cattle production in most tropical and subtropical areas of the world. Delayed skin hypersensitivity reactions are thought to cause Nguni cattle to be more resistant to R. microplus than Bonsmara cattle yet the cellular mechanisms responsible for these differences have not been classified. Tick counts and inflammatory cell infiltrates in skin biopsies from feeding sites of adult R. microplus ticks were determined in 9-month-old Nguni and Bonsmara heifers to determine the cellular mechanisms responsible for tick immunity. Nguni heifers (1.7 ± 0.03) had lower (P < 0.05) tick counts than the Bonsmaras (2.0 ± 0.03). Parasitized sites in Nguni heifers had higher counts of basophils, mast and mononuclear cells than those in the Bonsmara heifers. Conversely, parasitized sites in Nguni heifers had lower neutrophil and eosinophil counts than those in the Bonsmara heifers. Tick count was negatively correlated with basophil and mast cell counts and positively correlated with eosinophil counts in both breeds. In the Bonsmara breed, tick count was positively correlated with mononuclear cell counts. Cellular responses to adult R. microplus infestations were different and correlated with differences in tick resistance in Nguni and Bonsmara cattle breeds. It is essential to further characterise the molecular composition of the inflammatory infiltrate elicited by adult R. microplus infestation to fully comprehend immunity to ticks in cattle.
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